이혁진(李赫鎭) 교수
약학과[대학원] /의과대학 /약학부 /제약산업학과[대학원]
이혁진 교수는 약학대학 소속 약제학 및 물리약학 전공 교수이다. Johns Hopkins University (미), Columbia University (미) 및 KAIST에서 학/석/박사학위를 받았으며, 모더나 창업주인 MIT 대학의 Robert Langer 교수 지도 하에 siRNA 치료제 (Patisiran) 개발 및 핵산 구조체와 지질나노입자(LNP) 연구를 진행하였다. 2012년 본교 임용 후, 핵산 나노기술을 기반으로 한 차세대 RNA 핵산 치료제 (Dicer substrate RNA and IVT mRNA) 개발 및 체내 유전자 의약품 전달을 위한 3세대 지질나노입자(lipid nanoparticle) 발굴에 대한 연구를 진행하고 있다. 2013년 ~ 2014년 대한약학회 영문지 편집위원으로 활동하였으며, 2015년 ~ 2020년 공업화학회 영문지 편집위원, 그리고 2021년 Journal of Controlled Release 편집위원으로 활동 중이다. 현재까지 총 85여편의 논문을 SCI 국제학술지에 발표했다.
- 약학관 A동 306호
- 02-3277-3026
- 연구관심분야
- 약물전달 시스템, 유전자 치료제, 지질나노입자, 핵산 나노기술, mRNA
연구실적
- [학술지논문] Engineered ionizable lipid nanoparticles for targeted delivery of RNA therapeutics into different types of cells in the liver SCIENCE ADVANCES, 2021, v.7 no.9 , 4398-4398
- Development of Lipid Nanoparticle Formulation for the Repeated Administration of mRNA Therapeutics BIOMATERIALS RESEARCH, 2024, v.28, 17
- Effects of Histidine Oligomers in Lipid Nanoparticles on siRNA Delivery Macromolecular Bioscience, 2024, v.24 no.8, 2400043
- Oligonucleotide therapeutics and their chemical modification strategies for clinical applications Journal of Pharmaceutical Investigation, 2024, v.54 no.4, 415-433
- Optimization of polyethylene glycol shielding and mannose density on the lipid nanoparticles for efficient delivery to macrophages and spleens International Journal of Pharmaceutics, 2024, v.662, 124540
- Anti-glioma effect of ginseng-derived exosomes-like nanoparticles by active blood–brain-barrier penetration and tumor microenvironment modulation Journal of Nanobiotechnology, 2023, v.21 no.1, 253
- Efficient Delivery of Globotriaosylceramide Synthase siRNA using Polyhistidine-Incorporated Lipid Nanoparticles Macromolecular Bioscience, 2023, v.23 no.4, 2200423
- Engineered Lipid Nanoparticles for the Treatment of Pulmonary Fibrosis by Regulating Epithelial-Mesenchymal Transition in the Lungs Advanced Functional Materials, 2023, v.33 no.7, 2209432
- Immunogenicity of lipid nanoparticles and its impact on the efficacy of mRNA vaccines and therapeutics Experimental and Molecular Medicine, 2023, v.55 no.10, 2085-2096
- In vivo genome editing for hemophilia B therapy by the combination of rebalancing and therapeutic gene knockin using a viral and non-viral vector Molecular Therapy - Nucleic Acids, 2023, v.32, 161-172
- In vivo genome editing using 244-cis LNPs and low-dose AAV achieves therapeutic threshold in hemophilia A mice Molecular Therapy Nucleic Acids, 2023, v.34, 102050
- Lipid nanoparticles (LNPs) for in vivo RNA delivery and their breakthrough technology for future applications Advanced Drug Delivery Reviews, 2023, v.200, 114990
- Novel piperazine-based ionizable lipid nanoparticles allow the repeated dose of mRNA to fibrotic lungs with improved potency and safety Bioengineering and Translational Medicine, 2023, v.8 no.6, e10556
- Anisotropic Plasmonic Gold Nanorod-Indocyanine Green@Reduced Graphene Oxide-Doxorubicin Nanohybrids for Image-Guided Enhanced Tumor Theranostics ACS Omega, 2022, v.7 no.17, 15186-15199
- Artificial primary-miRNAs as a platform for simultaneous delivery of siRNA and antisense oligonucleotide for multimodal gene regulation Journal of Controlled Release, 2022, v.349, 983-991
- In vivo delivery of CRISPR-Cas9 using lipid nanoparticles enables antithrombin gene editing for sustainable hemophilia A and B therapy SCIENCE ADVANCES, 2022, v.8 no.3, eabj6901
- Protein-RNA interaction guided chemical modification of Dicer substrate RNA nanostructures for superior in vivo gene silencing Journal of Controlled Release, 2022, v.343, 57-65
- mRNA vaccines: the most recent clinical applications of synthetic mRNA Archives of Pharmacal Research, 2022, v.45 no.4, 245-262
- mRNA vaccines: the most recent clinical applications of synthetic mRNA Archives of Pharmacal Research, 2022, v.45 no.4, 245-262
- Engineered ionizable lipid nanoparticles for targeted delivery of RNA therapeutics into different types of cells in the liver SCIENCE ADVANCES, 2021, v.7 no.9, eabf4398
- Plasmon-Triggered Upconversion Emissions and Hot Carrier Injection for Combinatorial Photothermal and Photodynamic Cancer Therapy ACS APPLIED MATERIALS & INTERFACES, 2021, v.13 no.49, 58422-58433
- The core composition of DNA block copolymer micelles dictates DNA hybridization properties, nuclease stabilities, and cellular uptake efficiencies NANOSCALE, 2021, v.13 no.32, 13758-13763
- Adjuvant incorporated lipid nanoparticles for enhanced mRNA-mediated cancer immunotherapy BIOMATERIALS SCIENCE, 2020, v.8 no.4, 1101-1105
- Combined hybrid structure of siRNA tailed IVT mRNA (ChriST mRNA) for enhancing DC maturation and subsequent anticancer T cell immunity Journal of Controlled Release, 2020, v.327, 225-234
- Highly selective detection of single nucleotide polymorphism (SNP) using a dumbbell DNA probe with a gap-filling approach Journal of Industrial and Engineering Chemistry, 2020, v.88, 78-83
- Nanoformulated Single-Stranded RNA-Based Adjuvant with a Coordinative Amphiphile as an Effective Stabilizer: Inducing Humoral Immune Response by Activation of Antigen-Presenting Cells Angewandte Chemie - International Edition, 2020, v.59 no.28, 11540-11549
- Photocatalytic degradation of phenol using chemical vapor desposition graphene column Catalysts, 2020, v.10 no.11, 1-11
- The impaired redox balance in peroxisomes of catalase knockout mice accelerates nonalcoholic fatty liver disease through endoplasmic reticulum stress FREE RADICAL BIOLOGY AND MEDICINE, 2020, v.148, 22-32
- A dynamic DNA nanostructure with switchable and size-selective molecular recognition properties NANOSCALE, 2019, v.11 no.5, 2501-2509
- Capillary Tube Based Molecular Diagnostic Test for Naked Eye Detection of Antibiotic Resistant Bacteria Advanced Materials Technologies, 2019, v.4 no.1, 1800375
- Lamb wave-based molecular diagnosis using DNA hydrogel formation by rolling circle amplification (RCA) process Biosensors and Bioelectronics, 2019, v.142, 111496
- Membrane Fusion through the Generation of Triazole Ceramide via Click Chemistry at the Membrane Surface ASIAN JOURNAL OF ORGANIC CHEMISTRY, 2019, v.8 no.9, 1713-1717
- Multicistronic IVT mRNA for simultaneous expression of multiple fluorescent proteins Journal of Industrial and Engineering Chemistry, 2019, v.80, 770-777
- Tonsil-derived stem cells as a new source of adult stem cells WORLD JOURNAL OF STEM CELLS, 2019, v.11 no.8, 506-518
- Catalytic degradation of phenols by recyclable CVD graphene films NANOSCALE, 2018, v.10 no.13, 5840-5844
- Cellular uptake mechanism and comparative in vitro cytotoxicity studies of monomeric LMWP-siRNA conjugate Journal of Industrial and Engineering Chemistry, 2018, v.63, 103-111
- Development of mRNA vaccines and their prophylactic and therapeutic applications NANO RESEARCH, 2018, v.11 no.10, 5173-5192
- Emergence of synthetic mRNA: In vitro synthesis of mRNA and its applications in regenerative medicine BIOMATERIALS, 2018, v.156, 172-193
- Enhanced Chemical Reactivity of Graphene by Fermi Level Modulation CHEMISTRY OF MATERIALS, 2018, v.30 no.16, 5602-5609
- Enhanced intracellular delivery of macromolecules by melittin derivatives mediated cellular uptake Journal of Industrial and Engineering Chemistry, 2018, v.58, 290-295
- Enzymatic Synthesis of Self-assembled Dicer Substrate RNA Nanostructures for Programmable Gene Silencing NANO LETTERS, 2018, v.18 no.7, 4279-4284
- MMP-2-responsive fluorescent nanoprobes for enhanced selectivity of tumor cell uptake and imaging BIOMATERIALS SCIENCE, 2018, v.6 no.10, 2619-2626
- Mechanochemical synthesis of fluorescent carbon dots from cellulose powders NANOTECHNOLOGY, 2018, v.29 no.16
- Synergistic Nanozymetic Activity of Hybrid Gold Bipyramid-Molybdenum Disulfide Core@Shell Nanostructures for Two-Photon Imaging and Anticancer Therapy ACS Applied Materials and Interfaces, 2018, v.10 no.49, 42068-42076
- The cutting-edge technologies of siRNA delivery and their application in clinical trials ARCHIVES OF PHARMACAL RESEARCH, 2018, v.41 no.9, 867-874
- Aptamer-incorporated DNA Holliday junction for the targeted delivery of siRNA JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, 2017, v.56, 55-61
- Artificial Chemical Reporter Targeting Strategy Using Bioorthogonal Click Reaction for Improving Active-Targeting Efficiency of Tumor MOLECULAR PHARMACEUTICS, 2017, v.14 no.5, 1558-1570
- Effects of tumor microenvironments on targeted delivery of glycol chitosan nanoparticles Journal of Controlled Release, 2017, v.267, 223-231
- Extracellular matrix remodeling in vivo for enhancing tumor-targeting efficiency of nanoparticle drug carriers using the pulsed high intensity focused ultrasound Journal of Controlled Release, 2017, v.263, 68-78
- Hydrogel Based Biosensors for In Vitro Diagnostics of Biochemicals, Proteins, and Genes Advanced Healthcare Materials, 2017, v.6 no.12
- In vitro and in vivo behavior of DNA tetrahedrons as tumor-targeting nanocarriers for doxorubicin delivery COLLOIDS AND SURFACES B-BIOINTERFACES, 2017, v.157, 424-431
- A Highly Sensitive Molecular Detection Platform for Robust and Facile Diagnosis of Middle East Respiratory Syndrome (MERS) Corona Virus Advanced Healthcare Materials, 2016, 22 June 2016
- Bioorthogonal Copper Free Click Chemistry for Labeling and Tracking of Chondrocytes In Vivo Bioconjugate Chemistry, 2016, v.27 no.4, 927-936
- Bioreducible Cationic Poly(amido amine)s for Enhanced Gene Delivery and Osteogenic Differentiation of Tonsil-Derived Mesenchymal Stem Cells JOURNAL OF BIOMEDICAL NANOTECHNOLOGY, 2016, v.12 no.5, 1023-1034
- Dual delivery of biological therapeutics for multimodal and synergistic cancer therapies Advanced Drug Delivery Reviews, 2016, v.98, 113-133
- Gold-based hybrid nanomaterials for biosensing and molecular diagnostic applications BIOSENSORS & BIOELECTRONICS, 2016, v.80, 543-559
- Microfluidics-Based Pathogen Detection: A Highly Sensitive Molecular Detection Platform for Robust and Facile Diagnosis of Middle East Respiratory Syndrome (MERS) Corona Virus (Adv. Healthcare Mater. 17/2016) Advanced Healthcare Materials, 2016, v.5 no.17, 2146
- Near-infrared light-responsive nanomaterials for cancer theranostics Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, 2016, v.8 no.1, 23-45
- Non-invasive stem cell tracking in hindlimb ischemia animal model using bio-orthogonal copper-free click chemistry Biochemical and Biophysical Research Communications, 2016, v.479 no.4, 779-786
- Oligonucleotide-based biosensors for in vitro diagnostics and environmental hazard detection Analytical and Bioanalytical Chemistry, 2016, 18 JAN 2016, 1-24
- PEGylation and HAylation via catechol: alpha-Amine-specific reaction at N-terminus of peptides and proteins ACTA BIOMATERIALIA, 2016, v.43, 50-60
- Self-assembled mirror DNA nanostructures for tumor-specific delivery of anticancer drugs Journal of Controlled Release, 2016, v.243, 121-131
- Technological development of structural DNA/RNA-based RNAi systems and their applications ADVANCED DRUG DELIVERY REVIEWS, 2016, v.104, 29-43
- 고분자 전달체를 이용한 경폐 약물전달시스템 약 학 회 지, 2016, v.60 no.4, 173~179
- A fibrin-supported myocardial organ culture for isolation of cardiac stem cells via the recapitulation of cardiac homeostasis BIOMATERIALS, 2015, v.48, 66-83
- Cathepsin B Imaging to Predict Quality of Engineered Cartilage Macromolecular Bioscience, 2015, v.15 no.9, 1224-1232
- Co-delivery of VEGF and Bcl-2 dual-targeted siRNA polymer using a single nanoparticle for synergistic anti-cancer effects in vivo Journal of Controlled Release, 2015, 23 AUG 2015
- Dendrimeric siRNA for efficient gene silencing Angewandte Chemie - International Edition, 2015, v.54 no.23, 6740-6744
- DhITACT: DNA Hydrogel Formation by Isothermal Amplification of Complementary Target in Fluidic Channels ADVANCED MATERIALS, 2015, v.27 no.23, 3513-3517
- Induced myogenic commitment of human chondrocytes via non-viral delivery of minicircle DNA JOURNAL OF CONTROLLED RELEASE, 2015, v.200, 212-221
- Insulin induces phosphorylation of serine residues of translationally controlled tumor protein in 293T cells International Journal of Molecular Sciences, 2015, v.16 no.4, 7565-7576
- Nanoparticle-Based Combination Therapy for Cancer Treatment CURRENT PHARMACEUTICAL DESIGN, 2015, v.21 no.22, 3158-3166
- Near-infrared light-responsive nanomaterials for cancer theranostics Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, 2015, 2015
- Osteogenic priming of mesenchymal stem cells by chondrocyte-conditioned factors and mineralized matrix CELL AND TISSUE RESEARCH, 2015, v.362 no.1, 115-126
- Tonsil-derived Mesenchymal Stem Cells Ameliorate CCl4-induced Liver Fibrosis in Mice via Autophagy Activation SCIENTIFIC REPORTS, 2015, v.5
- 3D Culture of Tonsil-Derived Mesenchymal Stem Cells in Poly(ethylene glycol)-Poly(L-alanine-co-L-phenyl alanine) Thermogel ADVANCED HEALTHCARE MATERIALS, 2014, v.3 no.11, 1782-1791
- Biofunctional porous anodized titanium implants for enhanced bone regeneration JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 2014, v.102 no.10, 3639-3648
- Controlling mechanical properties of bio-inspired hydrogels by modulating nano-scale, inter-polymeric junctions BEILSTEIN JOURNAL OF NANOTECHNOLOGY, 2014, v.5, 887-894
- Efficient delivery of siRNAs by a photothermal approach using plant flavonoid-inspired gold nanoshells CHEMICAL COMMUNICATIONS, 2014, v.50 no.87, 13388-13390
- Erratum: Efficient delivery of siRNAs by a photothermal approach using plant flavonoid-inspired gold nanoshells (Chemical Communications (2014) DOI: 10.1039/c4cc07155g) Chemical Communications, 2014, v.50 no.88, 13616
- Gold nanoparticle (AuNP)-based drug delivery and molecular imaging for biomedical applications ARCHIVES OF PHARMACAL RESEARCH, 2014, v.37 no.1, 53-59
- Nanobiomaterials for pharmaceutical and medical applications ARCHIVES OF PHARMACAL RESEARCH, 2014, v.37 no.1, 1-3
- PH/redox/photo responsive polymeric micelle via boronate ester and disulfide bonds with spiropyran-based photochromic polymer for cell imaging and anticancer drug delivery European Polymer Journal, 2014, v.57, 1-10
- Pyrogallol 2-Aminoethane: A Plant Flavonoid-Inspired Molecule for Material-Independent Surface Chemistry ADVANCED MATERIALS INTERFACES, 2014, v.1 no.4
- Self-assembled DNA nanostructures prepared by rolling circle amplification for the delivery of siRNA conjugates CHEMICAL COMMUNICATIONS, 2014, v.50 no.86, 13049-13051
- Tunable and selective detection of cancer cells using a betainized zwitterionic polymer with BODIPY and graphene oxide NEW JOURNAL OF CHEMISTRY, 2014, v.38 no.6, 2225-2228
- Bio-inspired catechol chemistry: A new way to develop a re-moldable and injectable coacervate hydrogel Chemical Communications, 2012, v.48 no.97, 11895-11897
- Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery Nature Nanotechnology, 2012, v.7 no.6, 389-393
- [학술지논문] Engineered Lipid Nanoparticles for the Treatment of Pulmonary Fibrosis by Regulating Epithelial-Mesenchymal Transition in the Lungs ADVANCED FUNCTIONAL MATERIALS, 2023, v.33 no.7 , 2209432-2209432
- [지적재산권] TCTP-PTD를 포함하는 유전자 전달체 국내 : 특허, 등록, 10-1595152, 2016
- [지적재산권] 생분해성 중합체, 이의 제조 방법, 이를 포함하는 유전자 전달 시스템 국내 : 특허, 등록, 10-1577893, 2015
- [지적재산권] 표적 유전자 검출용 미세 유동 장치, 이의 제조방법 및 이를 이용한 검출 방법 국내 : 특허, 출원
- [지적재산권] 핵산 나노구조체의 대량생산방법 및 이의 약물전달체로서의 활용 국내 : 특허, 출원
- [지적재산권] 펩타이드 국내 : 특허, 등록
강의
-
2024-2학기
-
심화실습및연구Ⅰ
- 학수번호 37154분반 01
- 6학년 ( 4학점 , 200시간)
- 전공필수
-
심화실습및연구Ⅱ
- 학수번호 37155분반 01
- 6학년 ( 4학점 , 200시간)
- 전공필수
-
심화실습및연구Ⅲ
- 학수번호 37156분반 01
- 6학년 ( 4학점 , 200시간)
- 전공필수
-
물리약학Ⅱ
- 학수번호 38955분반 01
- 3학년 ( 1.5학점 , 1.5시간) 화 5~5 (약A104)
- 전공필수 약학전공 1~55
-
물리약학Ⅱ
- 학수번호 38955분반 02
- 3학년 ( 1.5학점 , 1.5시간) 화 2~2 (약A104)
- 전공필수 약학전공 56번 이후
-
물리약학Ⅱ
- 학수번호 39060분반 01
- 3학년 ( 1.5학점 , 1.5시간) 화 3~3 (약A104)
- 전공필수
-
-
2024-1학기
-
물리약학Ⅰ
- 학수번호 38946분반 01
- 3학년 ( 1.5학점 , 1.5시간) 화 2~2 (약A104)
- 전공필수 약학전공 1~48
-
물리약학Ⅰ
- 학수번호 38946분반 02
- 3학년 ( 1.5학점 , 1.5시간) 화 5~5 (약A104)
- 전공필수 약학전공 49번이후
-
산업약학입문
- 학수번호 39045분반 01
- 2학년 ( 1.5학점 , 1.5시간) 목 6~6 (약A100-1)
-
물리약학Ⅰ
- 학수번호 39051분반 01
- 3학년 ( 1.5학점 , 1.5시간) 화 3~3 (약A104)
- 전공필수
-
-
2023-2학기
-
물리약학Ⅱ 강의 계획서 상세보기
- 학수번호 37123분반 01
- 3학년 ( 1.5학점 , 1.5시간) 화 3~3 (약A104)
- 전공필수 학번 1-40
-
물리약학Ⅱ 강의 계획서 상세보기
- 학수번호 37123분반 02
- 3학년 ( 1.5학점 , 1.5시간) 화 2~2 (약A104)
- 전공필수 학번 41-80
-
물리약학Ⅱ 강의 계획서 상세보기
- 학수번호 37123분반 03
- 3학년 ( 1.5학점 , 1.5시간) 화 5~5 (약A104)
- 전공필수 학번 81-120
-
심화실습및연구Ⅰ 강의 계획서 상세보기
- 학수번호 37154분반 01
- 6학년 ( 4학점 , 200시간)
- 전공필수
-
심화실습및연구Ⅰ 강의 계획서 상세보기
- 학수번호 37154분반 02
- 6학년 ( 4학점 , 200시간)
- 전공필수
-
심화실습및연구Ⅱ 강의 계획서 상세보기
- 학수번호 37155분반 01
- 6학년 ( 4학점 , 200시간)
- 전공필수
-
심화실습및연구Ⅱ 강의 계획서 상세보기
- 학수번호 37155분반 02
- 6학년 ( 4학점 , 200시간)
- 전공필수
-
심화실습및연구Ⅲ 강의 계획서 상세보기
- 학수번호 37156분반 01
- 6학년 ( 4학점 , 200시간)
- 전공필수
-
심화실습및연구Ⅲ 강의 계획서 상세보기
- 학수번호 37156분반 02
- 6학년 ( 4학점 , 200시간)
- 전공필수
-
Honors research
- 학수번호 37803분반 01
- 4학년 ( 1학점 , 1시간)
-
약학전공설계프로젝트I 강의 계획서 상세보기
- 학수번호 38271분반 01
- 5학년 ( 3학점
- 추가 개설, 16기 도전학기 최종합격자에 한해 수강
-
나노의약품및제형개발
- 학수번호 G16896분반 01
- 학년 ( 3학점 , 3시간) 수 6~7 (약)
-
-
2023-1학기
-
물리약학I
- 학수번호 22535분반 01
- 3학년 ( 1.5학점 , 1.5시간) 화 2~2 (약A104)
- 전공필수 학번 1~40
-
물리약학I
- 학수번호 22535분반 02
- 3학년 ( 1.5학점 , 1.5시간) 화 3~3 (약A104)
- 전공필수 학번 41~80
-
물리약학I
- 학수번호 22535분반 03
- 3학년 ( 1.5학점 , 1.5시간) 화 5~5 (약A104)
- 전공필수 학번 81~120
-
약학연구입문 강의 계획서 상세보기
- 학수번호 38940분반 01
- 2학년 ( 1.5학점 , 1.5시간) 목 6~6 (약A404)
- 전공필수
-
산업약학입문 강의 계획서 상세보기
- 학수번호 39045분반 01
- 2학년 ( 1.5학점 , 1.5시간) 목 6~6 (약)
-
-
2022-2학기
-
물리약학Ⅱ
- 학수번호 37123분반 01
- 3학년 ( 1.5학점 , 1.5시간) 화 2~2 (약A400)
- 전공필수 학번 1~40
-
물리약학Ⅱ
- 학수번호 37123분반 02
- 3학년 ( 1.5학점 , 1.5시간) 목 5~5 (약A400)
- 전공필수 학번 41~80
-
물리약학Ⅱ
- 학수번호 37123분반 03
- 3학년 ( 1.5학점 , 1.5시간) 화 3~3 (약A400)
- 전공필수 학번 81~120
-
약학실습Ⅵ 강의 계획서 상세보기
- 학수번호 37138분반 01
- 5학년 ( 1.5학점 , 3시간) 월 6~9 (약A214)
- 전공필수 팀티칭,학번 1~22, 집중이수(8주) 수업
-
약학실습Ⅵ 강의 계획서 상세보기
- 학수번호 37138분반 02
- 5학년 ( 1.5학점 , 3시간) 화 6~9 (약A214)
- 전공필수 팀티칭,학번 23~43, 집중이수(8주) 수업
-
약학실습Ⅵ 강의 계획서 상세보기
- 학수번호 37138분반 03
- 5학년 ( 1.5학점 , 3시간) 수 6~9 (약A214)
- 전공필수 팀티칭,학번 44~65, 집중이수(8주) 수업
-
심화실습및연구Ⅰ
- 학수번호 37154분반 01
- 6학년 ( 4학점 , 200시간)
- 전공필수
-
심화실습및연구Ⅰ
- 학수번호 37154분반 02
- 6학년 ( 4학점 , 200시간)
- 전공필수
-
심화실습및연구Ⅱ
- 학수번호 37155분반 01
- 6학년 ( 4학점 , 200시간)
- 전공필수
-
심화실습및연구Ⅱ
- 학수번호 37155분반 02
- 6학년 ( 4학점 , 200시간)
- 전공필수
-
심화실습및연구Ⅲ
- 학수번호 37156분반 01
- 6학년 ( 4학점 , 200시간)
- 전공필수
-
심화실습및연구Ⅲ
- 학수번호 37156분반 02
- 6학년 ( 4학점 , 200시간)
- 전공필수
-
Honors research
- 학수번호 37803분반 01
- 4학년 ( 1학점 , 1시간)
- 팀티칭, 산업제약학과 02반과 합반
-
Lab rotation Ⅰ
- 학수번호 38927분반 01
- 1학년 ( 1.5학점 , 0시간) 목 7~7
- 팀티칭
-
Lab rotation Ⅰ
- 학수번호 38927분반 02
- 1학년 ( 1.5학점 목 7~7
- 팀티칭
-
Lab rotation Ⅰ
- 학수번호 39032분반 01
- 1학년 ( 1.5학점 , 0시간) 목 7~7
- 팀티칭
-
실무프로젝트분석II
- 학수번호 G16666분반 01
- 학년 ( 3학점 , 3시간) 화 8~9 (약)
-
신약개발세미나및실습IV
- 학수번호 G16889분반 01
- 학년 ( 3학점 , 3시간) 목 7~8 (약A400)
- 교수결정
-
신약개발세미나및실습Ⅳ
- 학수번호 G18241분반 01
- 학년 ( 3학점 , 3시간) 목 7~8 (약A400)
- 교수결정
-
-
2022-1학기
-
물리약학I
- 학수번호 22535분반 01
- 3학년 ( 1.5학점 , 1.5시간) 월 3~3 (약A104)
- 전공필수 팀티칭/학번 1~40
-
물리약학I
- 학수번호 22535분반 02
- 3학년 ( 1.5학점 , 1.5시간) 화 4~4 (약A404)
- 전공필수 팀티칭/학번 41~80
-
물리약학I
- 학수번호 22535분반 03
- 3학년 ( 1.5학점 , 1.5시간) 월 4~4 (약A104)
- 전공필수 팀티칭/학번 81~120/산업제약학과 04반과 합반
-
약물전달학
- 학수번호 36213분반 01
- 5학년 ( 1.5학점 , 1.5시간) 화 3~3 (약A400)
- 전공필수,영어강의 팀티칭(1~43번)
-
약물전달학
- 학수번호 36213분반 02
- 5학년 ( 1.5학점 , 1.5시간) 목 5~5 (약A404)
- 전공필수,영어강의 팀티칭(44~86번)
-
약물전달학
- 학수번호 36213분반 03
- 5학년 ( 1.5학점 , 1.5시간) 목 2~2 (약A400)
- 전공필수,영어강의 팀티칭(87~130) / 산업제약학과 04반과 합반
-
약물전달학
- 학수번호 36213분반 04
- 5학년 ( 1.5학점 , 1.5시간) 목 2~2 (약A400)
- 전공필수,영어강의 추가개설/약학과 03반과 합반
-
나노의약품및제형개발
- 학수번호 G16896분반 01
- 학년 ( 3학점 , 3시간) 수 5~6 (약)
-
-
2021-2학기
-
물리약학Ⅱ
- 학수번호 37123분반 01
- 3학년 ( 1.5학점 , 1.5시간) 화 3~3
- 전공필수,영어강의 학번 1~43
-
물리약학Ⅱ
- 학수번호 37123분반 02
- 3학년 ( 1.5학점 , 1.5시간) 목 5~5
- 전공필수,영어강의 학번 44~86
-
물리약학Ⅱ
- 학수번호 37123분반 03
- 3학년 ( 1.5학점 , 1.5시간) 목 4~4
- 전공필수,영어강의 학번 87~130, 산업제약학과 04반과 합반
-
물리약학Ⅱ
- 학수번호 37123분반 04
- 3학년 ( 1.5학점 , 1.5시간) 목 4~4
- 전공필수,영어강의 약학과 03반과 합반
-
약학실습Ⅵ
- 학수번호 37138분반 01
- 5학년 ( 1.5학점 , 3시간) 월 6~9 (약A214)
- 전공필수 집중이수(8주) 수업, 팀티칭,학번 1~22
-
약학실습Ⅵ
- 학수번호 37138분반 02
- 5학년 ( 1.5학점 , 3시간) 화 6~9 (약A214)
- 전공필수 집중이수(8주) 수업, 팀티칭,학번 23~43
-
약학실습Ⅵ
- 학수번호 37138분반 03
- 5학년 ( 1.5학점 , 3시간) 수 6~9 (약A214)
- 전공필수 집중이수(8주) 수업, 팀티칭,학번 44~65
-
심화실습및연구Ⅲ
- 학수번호 37156분반 02
- 6학년 ( 4학점
- 전공필수
-
Honors research
- 학수번호 37803분반 01
- 4학년 ( 1학점 , 1시간)
- 산업제약학과 02분반과 합반
-
-
2021-1학기
-
물리약학I
- 학수번호 22535분반 01
- 3학년 ( 1.5학점 , 1.5시간) 월 4~4
- 전공필수,영어강의 팀티칭/학번1~43
-
물리약학I
- 학수번호 22535분반 02
- 3학년 ( 1.5학점 , 1.5시간) 화 3~3
- 전공필수,영어강의 팀티칭/학번 44~86
-
물리약학I
- 학수번호 22535분반 03
- 3학년 ( 1.5학점 , 1.5시간) 화 5~5
- 전공필수,영어강의 팀티칭/학번87~130/산업제약학과 04반과 합반
-
물리약학I
- 학수번호 22535분반 04
- 3학년 ( 1.5학점 , 1.5시간) 화 5~5
- 전공필수,영어강의 약학과 03반과 합반
-
약물전달학
- 학수번호 36213분반 01
- 5학년 ( 1.5학점 , 1.5시간) 수 4~4
- 전공필수,영어강의 팀티칭(1~43번)
-
약물전달학
- 학수번호 36213분반 02
- 5학년 ( 1.5학점 , 1.5시간) 목 3~3
- 전공필수,영어강의 팀티칭(44~86번)
-
약물전달학
- 학수번호 36213분반 03
- 5학년 ( 1.5학점 , 1.5시간) 수 2~2
- 전공필수,영어강의 팀티칭(87~130)
-
나노의약품및제형개발
- 학수번호 G16896분반 01
- 학년 ( 3학점 , 3시간) 화 6~7 (약)
- 영어강의
-
학력
한국과학기술원 Ph.D.(생명과학)
Columbia University M.S.(Engin. & Appl. Sci.)
Johns Hopkins University B.S.(Biomedical Engin.)
경력
Massachusetts Institute of Technology, Post-doc. 2010-03-01 ~ 2012-02-29
연구분야
Advanced Biomaterials and Drug Delivery
1. Sustained release of protein drugs,
2. Novel regio-specific PEGylation for therapeutic proteins,
3. Natural polymer based hydrogels for cell therapy and drug delivery.
4. Preparation of Induced Pluripotent Stem (IPS) cells by non-viral gene delivery systems
It is important that our materials are designed to be non-cytotoxic, non-immunogenic, and biodegradable.
NanoBio and Theragnosis Technology
1. Gene Delivery System (pDNA, mRNA, and siRNA delivery)
2. Anti-Cancer Drug Delivery System (water insoluble small molecule delivery)
3. Molecular Imaging System (ROS sensing, ECM degrading enzyme sensitive imaging probe)
4. Inorganic nanoparticles for biomedical sensors and probes
Nucleic Acid Nanotechnology
1. Programmable Self-assembly of DNA/RNA Nanoparticles
2. Self-replicating Nucleic Acid Nanoparticles
3. Screening of Targeting Ligands as well as evaluating Cell Penetrating Peptides
4. Dip-pen Nano-lithography using DNA/RNA molecular ink