Eok-Soo Oh Professor
Life Sciences/Life Sciences
Dr. Eok-Soo Oh, Professor at the department of life sciences and Plural professor in Scranton College, received his Ph.D. degree in cell biology from the University of Alabama at Birmingham. He completed postdoctoral training at the Harvard Medical School and joined the faculty at Ewha Womans University in 1999. Dr. Oh's research program focuses on ‘Oncogenic signaling networks in tumor microenvironment’ and ‘Diagnosis and treatment of cancer’. He has published approximately 90 papers in related SCI journals and actively involved in diverse academic activities both domestically and internationally. In addition to being the Editor of ‘J Histochem Cytochem’ and ‘Scientifica’, he is on the Editorial Board of ‘Mol. Cells’, ‘BMB reports’ and ‘Int. J. Cell Biol’ as a guest editor. He served as the Director of the Business Incubation Center, and currently is President of ‘Office of Research’ and President of ‘Ewha University-Industry Collaboration Foundation’.
- Science Building C #306
- 02-3277-3761
- Office hours
- 월(9-12 시), 금 (2-5 시)
Research Record
- Emerging role of syndecans in maintaining homeostasis of colon epithelium during inflammation American Journal of Physiology - Cell Physiology, 2022, v.322 no.5, C960-C966
- Shed syndecan-2 enhances colon cancer progression by increasing cooperative angiogenesis in the tumor microenvironment Matrix Biology, 2022, v.107, 40-58
- Substituted Syndecan-2-Derived Mimetic Peptides Show Improved Antitumor Activity over the Parent Syndecan-2-Derived Peptide International Journal of Molecular Sciences, 2022, v.23 no.11, 5888
- Colocalization with MMP-7 in the Distal Colon is Crucial for Syndecan-2 Shedding in Dextran Sulfate Sodium-Induced Colitis Mice JOURNAL OF INFLAMMATION RESEARCH, 2021, v.14, 4987-5000
- Extracellular Vesicles from Korean Codium fragile and Sargassum fusiforme Negatively Regulate Melanin Synthesis MOLECULES AND CELLS, 2021, v.44 no.10, 736-745
- Fam188b downregulation sensitizes lung cancer cells to anoikis via egfr downregulation and inhibits tumor metastasis in vivo Cancers, 2021 , 1-15
- Syndecan transmembrane domain specifically regulates downstream signaling events of the transmembrane receptor cytoplasmic domain International Journal of Molecular Sciences, 2021, v.22 no.15, 7918
- D-tyrosine adds an anti-melanogenic effect to cosmetic peptides Scientific Reports, 2020, v.10 no.1, 262
- Emerging Role of Syndecans in Extracellular Matrix Remodeling in Cancer Journal of Histochemistry and Cytochemistry, 2020, v.68 no.12, 863-870
- The oligomerization mediated by the alanine 397 residue in the transmembrane domain is crucial to sydecan-3 functions Cellular Signalling, 2020, v.69, 109544
- Therapeutic potential of chemically modified mir-489 in triple-negative breast cancers Cancers, 2020, v.12 no.8, 1-16
- Proteoglycans and glycosaminoglycans as regulators of cancer stem cell function and therapeutic resistance FEBS JOURNAL, 2019, v.286 no.15, 2870-2882
- Tannic acid attenuates the formation of cancer stem cells by inhibiting NF-kappa B-mediated phenotype transition of breast cancer cells AMERICAN JOURNAL OF CANCER RESEARCH, 2019, v.9 no.8, 1664-
- The melanocortin-1 receptor reversely regulates the melanin synthesis and migration of melanoma cells via dimerization-induced conformational changes Biochemical and Biophysical Research Communications, 2019, v.518 no.4, 739-745
- Tyrosine 51 residue of the syndecan-2 extracellular domain is involved in the interaction with and activation of pro-matrix metalloproteinase-7 Scientific Reports, 2019, v.9 no.1, 10625
- Up-regulation of syndecan-2 in proximal colon correlates with acute inflammation FASEB JOURNAL, 2019, v.33 no.10, 11381-11395
- D-tyrosine negatively regulates melanin synthesis by competitively inhibiting tyrosinase activity PIGMENT CELL & MELANOMA RESEARCH, 2018, v.31 no.3, 374-383
- Keratinocytes negatively regulate the N-cadherin levels of melanoma cells via contact-mediated calcium regulation BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, v.503 no.2, 615-620
- Syndecan transmembrane domain modulates intracellular signaling by regulating the oligomeric status of the cytoplasmic domain CELLULAR SIGNALLING, 2018, v.52, 121-126
- Inflammatory hypoxia induces syndecan-2 expression through IL-1 beta-mediated FOXO3a activation in colonic epithelia FASEB JOURNAL, 2017, v.31 no.4, 1516-1530
- Lipopolysaccharide (LPS)-stimulated iNOS induction is increased by glucosamine under normal glucose conditions but is inhibited by glucosamine under high glucose conditions in macrophage cells Journal of Biological Chemistry, 2017, v.292 no.5, 1724-1736
- Metformin ameliorates the Phenotype Transition of Peritoneal Mesothelial Cells and Peritoneal Fibrosis via a modulation of Oxidative Stress Scientific Reports, 2017, v.7 no.1
- Processing of syndecan-2 by matrix metalloproteinase-14 and effect of its cleavage on VEGF-induced tube formation of HUVECs Biochemical Journal, 2017, v.474 no.22, 3719-3732
- Screening of breast cancer stem cell inhibitors using a protein kinase inhibitor library Cancer Cell International, 2017, v.17 no.1
- Syndecan-2 cytoplasmic domain up-regulates matrix metalloproteinase-7 expression via the protein kinase C gamma-mediated FAK/ERK signaling pathway in colon cancer JOURNAL OF BIOLOGICAL CHEMISTRY, 2017, v.292 no.39, 16321-16332
- Cytokeratin 18 is necessary for initiation of TGF-β1-induced epithelial–mesenchymal transition in breast epithelial cells Molecular and Cellular Biochemistry, 2016, v.423 no.42737, 21-28
- FK506 positively regulates the migratory potential of melanocyte-derived cells by enhancing syndecan-2 expression Pigment Cell and Melanoma Research, 2016, v.29 no.4, 434-443
- FK506 regulates pigmentation by maturing the melanosome and facilitating their transfer to keratinocytes Pigment Cell and Melanoma Research, 2016, v.29 no.2, 199-209
- Minireview: Syndecans and their crucial roles during tissue regeneration FEBS Letters, 2016, v.590
- New structural insight of C-terminal region of Syntenin-1, enhancing the molecular dimerization and inhibitory function related on Syndecan-4 signaling SCIENTIFIC REPORTS, 2016, v.6
- Syndecan-2 enhances E-cadherin shedding and fibroblast-like morphological changes by inducing MMP-7 expression in colon cancer cells Biochemical and Biophysical Research Communications, 2016, v.477 no.1, 47-53
- The conserved phenylalanine in the transmembrane domain enhances heteromeric interactions of syndecans Journal of Biological Chemistry, 2016, v.291 no.2, 872-881
- (E)-4-(3,4-Dimethoxyphenyl)but-3-en-1-ol Enhances Melanogenesis through Increasing Upstream Stimulating Factor-1-Mediated Tyrosinase Expression PLOS ONE, 2015, v.10 no.11
- A Unique Phenylalanine in the Transmembrane Domain Strengthens Homodimerization of the Syndecan-2 Transmembrane Domain and Functionally Regulates Syndecan-2 JOURNAL OF BIOLOGICAL CHEMISTRY, 2015, v.290 no.9, 5772-5782
- A combination of excimer laser treatment and topical tacrolimus is more effective in treating vitiligo than either therapy alone for the initial 6 months, but not thereafter Clinical and Experimental Dermatology, 2015, 24 Aug 2015
- Baicalin and baicalein inhibit transforming growth factor-β1-mediated epithelial-mesenchymal transition in human breast epithelial cells Biochemical and Biophysical Research Communications, 2015, v.458 no.3
- Endoplasmic reticulum stress as a novel target to ameliorate epithelial-to-mesenchymal transition and apoptosis of human peritoneal mesothelial cells Laboratory Investigation, 2015, v.95 no.10, 1157-1173
- Osteopontin mediates tumorigenic transformation of a preneoplastic murine cell line by suppressing anoikis: An Arg-Gly-Asp-dependent-focal adhesion kinase-caspase-8 axis Molecular Carcinogenesis, 2015, v.54 no.5, 379-392
- Shed syndecan-2 enhances tumorigenic activities of colon cancer cells ONCOTARGET, 2015, v.6 no.6, 3874-3886
- Trans-regulation of syndecan functions by hetero-oligomerization Journal of Biological Chemistry, 2015, v.290 no.27, 16943-16953
- Interleukin-1 alpha, promotes extracellular shedding of syndecan-2 via induction of matrix metalloproteinase-7 expression BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2014, v.446 no.2, 487-492
- Keratinocyte-derived laminin-332 protein promotes melanin synthesis via regulation of tyrosine uptake Journal of Biological Chemistry, 2014, v.289 no.31, 21751-21759
- Matrix metalloproteinase-14 mediates cleavage of syndecan-2 INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2014, v.34, S128-S128
- Syndecan-2 regulates melanin synthesis via protein kinase C beta II-mediated tyrosinase activation PIGMENT CELL & MELANOMA RESEARCH, 2014, v.27 no.3, 387-397
- Uric acid induces fat accumulation via generation of endoplasmic reticulum stress and SREBP-1c activation in hepatocytes LABORATORY INVESTIGATION, 2014, v.94 no.10, 1114-1125
- [학술지논문] Antifungal Activity of Bulgarian Rose Damascena Oil against Vaginitis-Causing Opportunistic Fungi Evid Based Complement Alternat Med, 2023, v.1 no.1 , 5054865-5054871
- [학술지논문] Synergistic Anti-Inflammatory Effects of Ethanol Extracts from Chrysanthemum zawadskii Flower and Cudrania tricuspidata Fruit Occur via Inhibition of the NF- κ B Signaling Pathway Evid Based Complement Alternat Med., 2023, v.22 no.1 , 1-9
- [학술지논문] Emerging role of syndecans in maintaining homeostasis of colon epithelium during inflammation AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2022, v.322 no.5 , C960-C966
- [학술지논문] Substituted Syndecan-2-Derived Mimetic Peptides Show Improved Antitumor Activity over the Parent Syndecan-2-Derived Peptide INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, v.23 no.11 , 5888-5888
- [학술지논문] Colocalization with MMP-7 in the Distal Colon is Crucial for Syndecan-2 Shedding in Dextran Sulfate Sodium-Induced Colitis Mice Journal of Inflammation Research, 2021, v.14 no.0 , 4987-5000
- [학술지논문] Extracellular Vesicles from Korean Codium fragile and Sargassum fusiforme Negatively Regulate Melanin Synthesis MOLECULES AND CELLS, 2021, v.44 no.10 , 736-745
- [학술지논문] FAM188B Downregulation Sensitizes Lung Cancer Cells to Anoikis via EGFR Downregulation and Inhibits Tumor Metastasis In Vivo CANCERS, 2021, v.13 no.2 , 247-247
- [학술지논문] Syndecan Transmembrane Domain Specifically Regulates Downstream Signaling Events of the Transmembrane Receptor Cytoplasmic Domain INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, v.22 no.15 , 7918-7918
- [학술지논문] D-tyrosine adds an anti-melanogenic effect to cosmetic peptides SCIENTIFIC REPORTS, 2020, v.10 no.1 , 262-262
- [학술지논문] Emerging Role of Syndecans in Extracellular Matrix Remodeling in Cancer JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, 2020, v.68 no.12 , 863-870
- [학술지논문] The oligomerization mediated by the alanine 397 residue in the transmembrane domain is crucial to sydecan-3 functions CELLULAR SIGNALLING, 2020, v.69 no.1 , 109544-109556
- [학술지논문] Therapeutic Potential of Chemically Modified miR-489 in Triple-Negative Breast Cancers CANCERS, 2020, v.12 no.8 , 2209-2209
- [학술지논문] Proteoglycans and glycosaminoglycans as regulators of cancer stem cell function and therapeutic resistance FEBS JOURNAL, 2019, v.286 no.15 , 2870-2882
- [학술지논문] Tannic acid attenuates the formation of cancer stem cells by inhibiting NF-kappa B-mediated phenotype transition of breast cancer cells AMERICAN JOURNAL OF CANCER RESEARCH, 2019, v.9 no.8 , 1664-1664
- [학술지논문] The melanocortin-1 receptor reversely regulates the melanin synthesis and migration of melanoma cells via dimerization-induced conformational changes BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2019, v.518 no.4 , 739-745
- [학술지논문] Tyrosine 51 residue of the syndecan-2 extracellular domain is involved in the interaction with and activation of pro-matrix metalloproteinase-7 SCIENTIFIC REPORTS, 2019, v.9 no.1 , 10625-10625
- [학술지논문] Up-regulation of syndecan-2 in proximal colon correlates with acute inflammation FASEB JOURNAL, 2019, v.33 no.10 , 11381-11395
- [저역서] Syndecan-2 Biology and Its Role in Colorectal Carcinoma Springer, 2022, 493
Courses
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2024-1st
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Cell Biology Ⅰ
- Subject No 34229Class No 01
- 3Year ( 3Credit , 3Hour) Tue 6~6 (POSCO361) , Thu 4~4 (POSCO361)
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Cell Biology Ⅰ
- Subject No 34229Class No 03
- 3Year ( 3Credit , 3Hour) Tue 3~3 (POSCO366) , Thu 2~2 (POSCO366)
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Experiments in Life Sciences Ⅲ
- Subject No 35313Class No 01
- 3Year ( 2Credit , 3Hour) Thu 6~7 (SCI-AA202)
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Experiments in Life Sciences Ⅲ
- Subject No 35313Class No 02
- 3Year ( 2Credit , 3Hour) Fri 6~7 (SCI-AA202)
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Cell Biology of Tissues
- Subject No 37121Class No 01
- 4Year ( 3Credit , 3Hour) Tue 4~4 (POSCO366) , Fri 5~5 (POSCO366)
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Special Topics in Cell Biology Ⅱ
- Subject No G16951Class No 01
- Year ( 3Credit , 3Hour) Fri 7~8 (SCI-C)
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Cancer Biology
- Subject No G16978Class No 01
- Year ( 3Credit , 3Hour) Tue 5~6 (SCI-C)
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2023-2nd
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General Biology 강의 계획서 상세보기
- Subject No 20412Class No 03
- 1Year ( 3Credit , 3Hour) Mon 6~6 (SCI-AA) , Wed 5~5 (102)
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General Biology: Laboratory Work Ⅱ 강의 계획서 상세보기
- Subject No 33333Class No 02
- 1Year ( 1Credit , 1.5Hour) Mon 7~8 (SCI-AA203)
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Cell Biology II 강의 계획서 상세보기
- Subject No 34237Class No 01
- 3Year ( 3Credit , 3Hour) Tue 2~2 (POSCO361) , Fri 3~3 (POSCO361)
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Introduction to Cancer Biology 강의 계획서 상세보기
- Subject No 38220Class No 01
- 4Year ( 3Credit , 3Hour) Tue 4~4 (POSCO453) , Fri 5~5 (POSCO453)
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Research for Life ScienceⅣ
- Subject No G16935Class No 01
- Year ( 3Credit , 3Hour)
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Special Topics in Cell BiologyⅠ
- Subject No G16950Class No 01
- Year ( 3Credit , 3Hour) Fri 4~5 (SCI-C)
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Advanced Cell Biology
- Subject No G16993Class No 01
- Year ( 3Credit , 3Hour) Tue 7~8 (SCI-C)
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2023-1st
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General Biology 강의 계획서 상세보기
- Subject No 20412Class No 03
- 1Year ( 3Credit , 3Hour) Mon 2~2 (POSCO453) , Thu 3~3 (POSCO453)
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Cell Biology I 강의 계획서 상세보기
- Subject No 34229Class No 01
- 3Year ( 3Credit , 3Hour) Tue 6~6 (POSCO361) , Thu 4~4 (POSCO361)
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Cell Biology I 강의 계획서 상세보기
- Subject No 34229Class No 02
- 3Year ( 3Credit , 3Hour) Tue 4~4 (POSCO366) , Fri 5~5 (POSCO366)
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Cell Biology of Tissues 강의 계획서 상세보기
- Subject No 37121Class No 01
- 4Year ( 3Credit , 3Hour) Wed 3~3 (POSCO366) , Fri 2~2 (POSCO366)
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Bioindustury in the 21st Century 강의 계획서 상세보기
- Subject No 37713Class No 01
- 4Year ( 1Credit , 1Hour) Wed 6~6 (POSCO363)
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Special Topics in Cell BiologyⅡ
- Subject No G16951Class No 01
- Year ( 3Credit , 3Hour) Fri 5~6 (SCI-C)
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Bio Technology
- Subject No G16974Class No 01
- Year ( 3Credit , 3Hour) Wed 5~6 (SCI-C)
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2022-2nd
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General Biology: Laboratory Work II
- Subject No 33333Class No 01
- 1Year ( 1Credit , 1.5Hour) Mon 6~7 (SCI-AA202)
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General Biology: Laboratory Work II
- Subject No 33333Class No 02
- 1Year ( 1Credit , 1.5Hour) Wed 6~7 (SCI-AA202)
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Cell Biology II
- Subject No 34237Class No 01
- 3Year ( 3Credit , 3Hour) Tue 6~6 (POSCO361) , Thu 4~4 (POSCO361)
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Introduction to Cancer Biology
- Subject No 38220Class No 01
- 4Year ( 3Credit , 3Hour) Tue 4~4 (POSCO453) , Fri 5~5 (POSCO453)
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Life Science SeminarⅣ
- Subject No G16931Class No 01
- Year ( 3Credit , 3Hour) Thu 3~4 (SCI-C)
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Research for Life ScienceⅣ
- Subject No G16935Class No 01
- Year ( 3Credit , 3Hour)
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Advanced Cell Biology
- Subject No G16993Class No 01
- Year ( 3Credit , 3Hour) Tue 7~8 (SCI-C)
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2022-1st
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General Biology
- Subject No 20412Class No 02
- 1Year ( 3Credit , 3Hour) Tue 3~3 (POSCO453) , Thu 2~2 (POSCO453)
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Cell Biology I
- Subject No 34229Class No 01
- 3Year ( 3Credit , 3Hour) Tue 6~6 (POSCO452) , Thu 4~4 (POSCO452)
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Cell Biology I
- Subject No 34229Class No 02
- 3Year ( 3Credit , 3Hour) Wed 6~6 (POSCO366) , Fri 4~4 (POSCO366)
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Bio Technology
- Subject No G16974Class No 01
- Year ( 3Credit , 3Hour) Wed 5~6 (-)
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Cancer Biology
- Subject No G16978Class No 01
- Year ( 3Credit , 3Hour) Mon 5~6 (-)
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2021-2nd
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General Biology: Laboratory Work II
- Subject No 33333Class No 01
- 1Year ( 1Credit , 1.5Hour) Mon 6~7 (SCI-AA202)
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General Biology: Laboratory Work II
- Subject No 33333Class No 02
- 1Year ( 1Credit , 1.5Hour) Wed 6~7 (SCI-AA202)
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Cell Biology II
- Subject No 34237Class No 01
- 3Year ( 3Credit , 3Hour) Wed 3~3 , Fri 2~2
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Molecular Medical Science
- Subject No 36336Class No 01
- 4Year ( 3Credit , 3Hour) Tue 5~5 , Thu 6~6
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Introduction to Cancer Biology
- Subject No 38220Class No 01
- 4Year ( 3Credit , 3Hour) Tue 4~4 , Fri 5~5
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Life Science SeminarⅡ
- Subject No G16929Class No 01
- Year ( 3Credit , 3Hour) Thu 3~4 (SCI-C)
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Research for Life ScienceⅣ
- Subject No G16935Class No 01
- Year ( 3Credit , 3Hour)
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Advanced Cell Biology
- Subject No G16993Class No 01
- Year ( 3Credit , 3Hour) Tue 7~8 (SCI-C)
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