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Ewha University

College of Science & Industry Convergence

Yoon Jung Park Professor

Department of Nutritional Science & Food Management/

박윤정 프로필 사진
Dr. Yoon Jung Park is a Professor at the Department of Nutritional Science and Food Management, College of Health Science, where she is heading the Epigenetics lab. She got her Ph.D. from the Division of Nutritional Sciences at Cornell University (Dr. Paul Soloway Lab), followed by a postdoctoral training at the German Cancer Research Center in Heidelberg (Dr. Christoph Plass lab),  with the support of a Roman Herzog Research Fellowship. Her research is focused on the mechanisms by which environmental factors such as diets epigenetically influence cells, tissues, or organisms and by which the epigenetic changes are transmitted to subsequent generations using multiomics data, including genomics, transcriptomics, epigenomics, metabolomics, and microbiome analysis. Through years of international research experiences, she maintains close foreign collaborations. She has published in high-ranking journals, including Nature Medicine, EMBO Molecular Medicine, PLoS Genetics, and Molecular Cell. Current projects are the followings: 1) Epigenetic mechanisms underlying inheritance of metabolic imprinting, 2) Effects of macronutrients on Circadian clock regulation, and 3) Omics analysis on diabetes and cancer to identify biomarkers.
  • Human Ecology Building (Morris Hall) #307
  • 02-3277-6533
  • Research Interests
Research Record
  • Alterations in cardiac DNA methylation in human dilated cardiomyopathy EMBO Molecular Medicine, 2013, v.5 no.3, 413-429
    SCIE Scopus dColl.
  • BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1 Nature Medicine, 2013, v.19 no.7, 901-908
    SCIE Scopus dColl.
  • Association between use of vitamin and mineral supplement and non-alcoholic fatty liver disease in hypertensive adults Scientific Reports, 2023, v.13 no.1, 13670
    SCIE Scopus dColl.
  • Association of NAFLD with FGF21 Polygenic Hazard Score, and Its Interaction with Protein Intake Level in Korean Adults Nutrients, 2023, v.15 no.10, 2385
    SCIE Scopus dColl.
  • Meal-Based Intervention on Health Promotion in Middle-Aged Women: A Pilot Study Nutrients, 2023, v.15 no.9, 2108
    SCIE Scopus dColl.
  • Short-Term Effects of Weight-Loss Meal Replacement Programs with Various Macronutrient Distributions on Gut Microbiome and Metabolic Parameters: A Pilot Study Nutrients, 2023, v.15 no.22, 4744
    SCIE Scopus dColl.
  • [학술지논문] protein restriction in metabolic health: lessons from rodent models NUTRIENTS, 2024, v.16 no.229 , 1-15
    SCIE
  • [학술지논문] Association between use of vitamin and mineral supplement and non-alcoholic fatty liver disease in hypertensive adults SCIENTIFIC REPORTS, 2023, v.13 no.1 , 1-13
    SCIE
  • [학술지논문] Association of NAFLD with FGF21 Polygenic Hazard Score, and Its Interaction with Protein Intake Level in Korean Adults NUTRIENTS, 2023, v.15 no.10 , 2385-2385
    SCIE
  • [학술지논문] Associations of Food Insecurity with Dietary Inflammatory Potential and Risk of Low Muscle Strength NUTRIENTS, 2023, v.15 no.5 , 1-14
    SCIE
  • [학술지논문] Meal-Based Intervention on Health Promotion in Middle-Aged Women: A Pilot Study NUTRIENTS, 2023, v.15 no.9 , 2108-2108
    SCIE
  • [학술지논문] Short-Term Effects of Weight-Loss Meal Replacement Programs with Various Macronutrient Distributions on Gut Microbiome and Metabolic Parameters: A Pilot Study NUTRIENTS, 2023, v.15 no.22 , 1-16
    SCIE
  • [학술지논문] 2020 Korean Dietary Reference Intakes for Protein: Estimation of protein requirements and the status of dietary protein intake in the Korean population Journal of Nutrition and Health, 2022, v.55 no.1 , 10-20
    Scopus
  • [학술지논문] Effects of Korean Food-based Dietary Inflammatory Index Potential on the incidence of diabetes and HbA1c level in Korean adults aged 40 years and older Journal of Nutrition and Health, 2022, v.55 no.2 , 263-277
    Scopus
  • [학술지논문] A review of recent evidence of dietary protein intake and health NUTRITION RESEARCH AND PRACTICE, 2022, v.16 no.0 , S37-S46
    SCIE
  • [학술지논문] Adenosine derivatives from Cordyceps exert antitumor effects against ovarian cancer cells through ENT1-mediated transport, induction of AMPK signaling, and consequent autophagic cell death BIOMEDICINE & PHARMACOTHERAPY, 2022, v.153 no.0 , 113491-113491
    SCI
  • [학술지논문] Association between Use of Nutrition Labels and Risk of Chronic Kidney Disease: The Korean National Health and Nutrition Examination Survey (KNHANES) 2008-2019 NUTRIENTS, 2022, v.14 no.9 , 1731-1731
    SCIE
  • [학술지논문] Effects of Dietary Fat to Carbohydrate Ratio on Obesity Risk Depending on Genotypes of Circadian Genes NUTRIENTS, 2022, v.14 no.3 , 478-478
    SCIE
  • [학술지논문] The Anticancer Effect of Natural Plant Alkaloid Isoquinolines INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, v.22 no.4 , 1653-1653
    SCIE
  • [학술지논문] EHMT2 Inhibition Induces Cell Death in Human Non-Small Cell Lung Cancer by Altering the Cholesterol Biosynthesis Pathway INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, v.21 no.3 , 1002-1002
    SCIE
  • [학술지논문] Effects of Coffee Intake on Dyslipidemia Risk According to Genetic Variants in the ADORA Gene Family among Korean Adults NUTRIENTS, 2020, v.12 no.2 , 493-493
    SCIE
  • [학술지논문] Globally altered epigenetic landscape and delayed osteogenic differentiation in H3.3-G34W-mutant giant cell tumor of bone NATURE COMMUNICATIONS, 2020, v.11 no.5414 , 1-16
    SCI
  • [학술지논문] Altered expression of inflammation-associated genes in the hypothalamus of obesity mouse models NUTRITION RESEARCH, 2019, v.70 no.Special SI , 40-49
    SCI
  • [학술지논문] Promotion of Cell Death in Cisplatin-Resistant Ovarian Cancer Cells through KDM1B-DCLRE1B Modulation INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019, v.20 no.10 , 2443-2443
    SCIE
  • [학술지논문] Diet-induced obesity leads to metabolic dysregulation in offspring via endoplasmic reticulum stress in a sex-specific manner INTERNATIONAL JOURNAL OF OBESITY, 2018, v.42 no.2 , 244-251
    SCI
  • [학술지논문] Links between Serine Biosynthesis Pathway and Epigenetics in Cancer Metabolism Clinical Nutrition Research, 2018, v.7 no.3 , 153-160
    KCI
  • [학술지논문] Silencing of peroxiredoxin II by promoter methylation is necessary for the survival and migration of gastric cancer cells EXPERIMENTAL AND MOLECULAR MEDICINE, 2018, v.50 no.1 , 1-13
    SCI
  • [학술지논문] The Anticancer Properties of Cordycepin and Their Underlying Mechanisms INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, v.19 no.10 , 3027-3027
    SCIE
  • [학술지논문] Transcriptome and protein interaction profiling in cancer cells with mutations in histone H3.3 SCIENTIFIC DATA, 2018, v.5 no.0 , 180283-180283
    SCIE
  • [학술지논문] Anti-cancer effect of Scutellaria baicalensis in combination with cisplatin in human ovarian cancer cell BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2017, v.17 no.277 , 1-10
    SCIE
  • [학술지논문] Epigenetics: Linking nutrition to molecular mechanisms in aging PREVENTIVE NUTRITION AND FOOD SCIENCE, 2017, v.22 no.2 , 81-89
    Scopus
  • [학술지논문] TET-mediated hydroxymethylcytosine at the Ppar gamma locus is required for initiation of adipogenic differentiation INTERNATIONAL JOURNAL OF OBESITY, 2017, v.41 no.4 , 652-659
    SCI
  • [학술지논문] The histone variant H3.3 G34W substitution in giant cell tumor of the bone link chromatin and RNA processing SCIENTIFIC REPORTS, 2017, v.7 no.13459 , 1-14
    SCI
  • [학술지논문] 2015 Korean Guidelines for the Management of Dyslipidemia: Executive Summary (English Translation) KOREAN CIRCULATION JOURNAL, 2016, v.46 no.3 , 275-306
    SCIE
  • [학술지논문] Association between consumption of milk and dairy products, calcium and riboflavin, and periodontitis in Korean adults: Using the 2007-2010 Korea National Health and Nutrition Examination Surveys JOURNAL OF NUTRITION AND HEALTH, 2014, v.47 no.4 , 258-267
    Scopus
  • [학술지논문] Can Proopiomelanocortin Methylation Be Used as an Early Predictor of Metabolic Syndrome? DIABETES CARE, 2014, v.37 no.3 , 734-739
    SCI
  • [학술지논문] Long Noncoding RNA TARID Directs Demethylation and Activation of the Tumor Suppressor TCF21 via GADD45A MOLECULAR CELL, 2014, v.55 no.4 , 604-614
    SCI
  • [학술지논문] 만 40세 성인의 우울기분과 생활습관과의 관계 JOURNAL OF THE KOREAN SOCIETY OF FOOD SCIENCE AND NUTRITION(한국식품영양과학회지), 2014, v.43 no.5 , 772-783
    Scopus
  • [학술지논문] Alterations in cardiac DNA methylation in human dilated cardiomyopathy EMBO MOLECULAR MEDICINE, 2013, v.5 no.3 , 413-429
    SCIE
  • [학술지논문] BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1 NATURE MEDICINE, 2013, v.19 no.7 , 901-+
    SCI
  • [학술지논문] Epigenetic biomarkers: a step forward for understanding periodontitis Journal of Periodontal & Implant Science, 2013, v.43 no.3 , 111-120
  • [학술지논문] Relationships between obesity, blood and urinary compositions, and dietary habits and depressed mood in Koreans at the age of 40, a life transition period Journal of Nutrition and Health, 2013, v.46 no.3 , 261-275
    Scopus
  • [저역서] 생활속의 영양학 교문사, 2023, 576
  • [저역서] Personalized epigenetics - Nutrigenomics: Personalized Nutrition meets Epigenetics Elsevier_Academic Press, 2015, 591
  • [학술발표] FGF21 polygenic hazard score and protein intake on risk of non-alcoholic fatty liver disease, 한국지질동맥경화학회 춘계학술대회, 대한민국, 2023-04-01 한국지질동맥경화학회 초록, 2023
  • [학술발표] Transcriptomics-based Exploration of Tissue-specific Biomarkers for Circadian Metabolic Regulation using the Time Restriction Feeding Model The Korea Nutrition Society International Conference , 대한민국, 2023-10-13 The Korea Nutrition Society International Conference , 2023
  • [학술발표] A Potential Mechanism Underlying Paternal Transmission of Diet-induced Metabolic Stress through Angiogenin-mediated tRNA fragmentation the 22nd IUNS-ICN International Congress of Nutrition , 일본, 2022-12-06 the 22nd IUNS-ICN International Congress of Nutrition , 2022
  • [학술발표] Butyrate-induced anti-obesity effects via changes in gut microbiome and muscle oxidative metabolism the 22nd IUNS-ICN International Congress of Nutrition , 일본, 2022-12-06 Proceeding of the 22nd IUNS-ICN International Congress of Nutrition , 2022
  • [학술발표] Effects of Nicotinamide Mononucleotide on Liver and Adipose tissue by Diet and Age 2022 International Conference of the Korean Nutrition Society, 대한민국, 2022-10-14 2022 International Conference of the Korean Nutrition Society, 2022
  • [학술발표] Effects of the weight-controlled meal plans with various macronutrient distributions on gut microbiome and metabolic changes 2022 International Conference of the Korean Nutrition Society, 대한민국, 2022-10-14 2022 International Conference of the Korean Nutrition Society, 2022
  • [학술발표] Precision Nutrition and Health Management: A Meal-based Intervention for Postmenopausal Women 2022 International Conference of the Korean Nutrition Society, 대한민국, 2022-10-14 2022 International Conference of the Korean Nutrition Society, 2022
  • [학술발표] Role of DDX5 on Adipogenesis via Altering the Splicing of Metabolic-related Genes 2022 International Conference of the Korean Nutrition Society, 대한민국, 2022-10-14 2022 International Conference of the Korean Nutrition Society, 2022
  • [학술발표] Alkbh5, an RNA demethylase, is involved in fine-tuning of cell differentiation Nutrition 2019 , 미국, 2019-06-09 Nutrition 2019 , 2019
  • [학술발표] Alkbh5, an RNA demethylase, was required for induction of myogenesis in the C2C12 cell model. 2019 International Conference of the Korean Nutrition Society , 대한민국, 2019-10-11 2019 International Conference of the Korean Nutrition Society , 2019
  • [학술발표] Anticancer effects of Cordyceps militaris extract in human ovarian cancer cells via ADORA2B. Nutrition 2019 , 미국, 2019-06-10 Nutrition 2019 by American Society for Nutrition , 2019
  • [학술발표] Chelidonium majus L extract reduce cell viability and c-Myc overexpression sensitize C majus L induced apoptosis. 2019 International Conference of the Korean Nutrition Society, 대한민국, 2019-10-11 2019 International Conference of the Korean Nutrition Society, 2019
  • [학술발표] Epigenetic marks on nucleic acids fine-tune cell differentiation as metabolic sensors. The Federation of European Nutrition Societies (FENS) 2019 Conference , 아일랜드, 2019-10-17 The Federation of European Nutrition Societies (FENS) 2019 Conference , 2019
  • [학술발표] Implementation and practice of nutrigenomics for precision medicine 2019 Annual conference of Korean Society of Clinical Nutrition , 대한민국, 2019-06-28 2019 Annual conference of Korean Society of Clinical Nutrition , 2019
  • [학술발표] Alteration of the TET2 gene and its expression are associated with higher proliferation and poor prognosis in NSCLC 한국영양학회 국제학술대회, 대한민국, 평창, 2018-10-18 한국영양학회 국제학술대회, 2018
  • [학술발표] Associations between Genetic Variants of Circadian Clock Genes, Nutrients Intake, and Susceptibility to Chronic Diseases International Conference of KFN annual meeting , 대한민국, 부산, 2018-11-01 International Conference of KFN annual meeting , 2018
  • [학술발표] Effects of Glutaminolysis on Proliferation of Non-small Lung Cancer Cell and its molecular mechanism International Conference of KFN annual meeting , 대한민국, 부산, 2018-11-01 International Conference of KFN annual meeting , 2018
  • [학술발표] Genetic Variants of Circadian Clock Genes influence risk of Chronic Diseases 12th International congress of ISNN, 캐나다, Manitoba, 2018-09-30 ISNN, 2018
  • [학술발표] Suppression of alkbh5 triggers adipogenic induction via regulating c/ebp 한국영양학회 국제학술대회, 대한민국, 평창, 2018-10-19 한국영양학회 국제학술대회, 2018
Courses
  • 2024-1st

    • First-Year Seminar

    • Human Nutrition for Living

      • Subject No 33418Class No 01
      • 1Year ( 3Credit , 3Hour) Tue 5~5 (ECOL511) , Thu 6~6 (ECOL511)
    • Comprehensive Review of Clinical Medicine I

      • Subject No 37640Class No 01
      • 3Year ( 2Credit , 45Hour)
      • Major Requisite
    • Epigenetics

      • Subject No G13194Class No 01
      • Year ( 3Credit , 3Hour) Thu 2~3 (ECOL607)
      • Language Changed
    • Introduction to System Health

      • Subject No G18067Class No 01
      • Year ( 3Credit , 3Hour) Thu 7~8
    • Introduction to System Health

      • Subject No G18441Class No 01
      • Year ( 3Credit , 3Hour) Thu 7~8
      • Professor Changed
  • 2023-2nd

    • Nutrigenomics and personalized nutrition (capstone design) 강의 계획서 상세보기

      • Subject No 37294Class No 01
      • 4Year ( 3Credit , 3Hour) Tue 4~4 (ECOL114) , Fri 5~5 (ECOL114)
    • Nutrient sensing and adaptation

      • Subject No G17727Class No 01
      • Year ( 3Credit , 3Hour) Wed 4~5 (ECOL607)
  • 2023-1st

    • Human Nutrition for Living

    • Molecular Biology and Signal Transduction in Nutrition

      • Subject No G17204Class No 01
      • Year ( 3Credit , 3Hour) Thu 2~3 (ECOL607)
    • Introduction to System Health 강의 계획서 상세보기

      • Subject No G18067Class No 01
      • Year ( 3Credit , 3Hour) Thu 7~8
    • Introduction to System Health

      • Subject No G18441Class No 01
      • Year ( 3Credit , 3Hour) Thu 7~8
  • 2022-2nd

    • Nutrigenomics and personalized nutrition (capstone design) 강의 계획서 상세보기

    • Epigenetics

      • Subject No G13194Class No 01
      • Year ( 3Credit , 3Hour) Thu 2~3 (ECOL607)
    • Current Technics in Nutritional Science

      • Subject No G17205Class No 01
      • Year ( 3Credit , 3Hour) Mon 2~3 (ECOL607)
  • 2022-1st

    • Human Nutrition for Living

      • Subject No 33418Class No 01
      • 1Year ( 3Credit , 3Hour) Tue 5~5 , Thu 6~6
    • Introduction to System Health

      • Subject No G18067Class No 01
      • Year ( 3Credit , 3Hour) Thu 7~8
  • 2021-2nd

    • Nutrigenomics and personalized nutrition (capstone design)

      • Subject No 37294Class No 01
      • 4Year ( 3Credit , 3Hour) Tue 5~5 , Thu 6~6
    • Nutrient sensing and adaptation

      • Subject No G17727Class No 01
      • Year ( 3Credit , 3Hour) Wed 2~3 (ECOL607)
  • 2021-1st

    • First-Year Seminar

    • Human Nutrition for Living

      • Subject No 33418Class No 01
      • 1Year ( 3Credit , 3Hour) Mon 4~4 , Thu 5~5
    • Introduction to System Health

      • Subject No G18067Class No 01
      • Year ( 3Credit , 3Hour) Thu 7~8
    • Omics Science

      • Subject No G18070Class No 01
      • Year ( 3Credit , 3Hour) Mon 5~6 (ECOL607)
      • Language Changed
Academic Background

Cornell University Ph.D.(Div. of nutritional science molecular nutrition)