안영호 교수는 의학전문대학원 의학과 분자의과학교실 소속 교수로, 서울대학교 생명과학부에서 박사학위를 받았으며, 미국 MD Anderson Cancer Center에서 박사후연구과정을 마쳤다. 폐암을 비롯한 다양한 암의 발생과 전이에 초점을 맞추어, 암세포 내의 신호전달과정, 마이크로 RNA가 종양의 발생 및 전이에 미치는 영향 등을 연구하고 있다. 현재까지 총 20여편의 논문을 <Journal of Clinical Investigation> 등 SCI급 국제 학술지에 발표했다.
miR-200-mediated inactivation of cancer-associated fibroblasts via targeting of NRP2-VEGFR signaling attenuates lung cancer invasion and metastasisMolecular Therapy Nucleic Acids, 2024, v.35 no.2, 102194
Effect of aging on the formation and growth of colonic epithelial organoids by changes in cell cycle arrest through TGF-β-Smad3 signalingInflammation and Regeneration, 2023, v.43 no.1, 35
Inhibition of STAT6 Activation by AS1517499 Inhibits Expression and Activity of PPARγ in Macrophages to Resolve Acute Inflammation in MiceBiomolecules, 2022, v.12 no.3, 447
Plasma Membrane Localization of CD36 Requires Vimentin Phosphorylation; A Mechanism by Which Macrophage Vimentin Promotes AtherosclerosisFRONTIERS IN CARDIOVASCULAR MEDICINE, 2022, v.9, 792717
Reprogramming of cancer-associated fibroblasts by apoptotic cancer cells inhibits lung metastasis via Notch1-WISP-1 signalingCellular and Molecular Immunology, 2022, v.19 no.12, 1373-1391
Transcriptional control of a collagen deposition and adhesion process that promotes lung adenocarcinoma growth and metastasisJCI Insight, 2022, v.7 no.1, e153948
MicroRNA-142-5p is Up-regulated on Allogeneic Immune Responses and Up-regulates MHC Class II Expression in Human Umbilical Vein Endothelial CellsTransplantation Proceedings, 2021, v.53 no.1, 408-416
Long non-coding RNAs as regulators of interactions between cancer-associated fibroblasts and cancer cells in the tumor microenvironmentInternational Journal of Molecular Sciences, 2020, v.21 no.20, 1-16
Programming of macrophages by UV-irradiated apoptotic cancer cells inhibits cancer progression and lung metastasisCellular and Molecular Immunology, 2019, v.16 no.11, 851-867
Repression of adenosine triphosphate–binding cassette transporter ABCG2 by estrogen increases intracellular glutathione in brain endothelial cells following ischemic reperfusion injuryNeurobiology of Aging, 2018, v.66, 138-148
Urinary Exosomal and cell-free DNA Detects Somatic Mutation and Copy Number Alteration in Urothelial Carcinoma of BladderScientific Reports, 2018, v.8 no.1, 14707
Epithelial-to-mesenchymal transition drives a pro-metastatic Golgi compaction process through scaffolding protein PAQR11JOURNAL OF CLINICAL INVESTIGATION, 2017, v.127 no.1, 117-131
Exogenous C2 ceramide suppresses matrix metalloproteinase gene expression by inhibiting ROS production and MAPK signaling pathways in PMA-stimulated human astroglioma cellsInternational Journal of Molecular Sciences, 2016, v.17 no.4
Liver X receptor and STAT1 cooperate downstream of Gas6/Mer to induce anti-inflammatory arginase 2 expression in macrophagesSCIENTIFIC REPORTS, 2016, v.6
Musashi-2 (MSI2) supports TGF-beta signaling and inhibits claudins to promote non-small cell lung cancer (NSCLC) metastasisPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2016, v.113 no.25, 6955-6960
Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppressionNATURE COMMUNICATIONS, 2014, v.5
[학술지논문] miR-200-mediated inactivation of cancer-associated fibroblasts via targeting of NRP2-VEGFR signaling attenuates lung cancer invasion and metastasis
MOLECULAR THERAPY-NUCLEIC ACIDS, 2024, v.35
no.2
, 102194-102194
SCIE
[학술지논문] Cancer-associated fibroblasts activated by miR-196a promote the migration and invasion of lung cancer cells
CANCER LETTERS, 2021, v.508
no.2021
, 92-103
SCI
[학술지논문] Diagnostic and Therapeutic Implications of microRNAs in Non-Small Cell Lung Cancer
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, v.21
no.22
, 8782-8782
SCIE
[학술지논문] Long Non-Coding RNAs as Regulators of Interactions between Cancer-Associated Fibroblasts and Cancer Cells in the Tumor Microenvironment
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, v.21
no.20
, 7484-7484
SCIE
[학술지논문] MiR-34a and miR-34b/c have distinct effects on the suppression of lung adenocarcinomas
EXPERIMENTAL AND MOLECULAR MEDICINE, 2019, v.51
no.0
, 9-9
SCI
[학술지논문] QKI, a miR-200 target gene, suppresses epithelial-to-mesenchymal transition and tumor growth
INTERNATIONAL JOURNAL OF CANCER, 2019, v.145
no.6
, 1585-1595
SCI
[학술지논문] Epithelial-to-mesenchymal transition drives a pro-metastatic Golgi compaction process through scaffolding protein PAQR11
JOURNAL OF CLINICAL INVESTIGATION, 2017, v.127
no.1
, 117-131
SCI
[학술지논문] MKK4 activates non-canonical NF kappa B signaling by promoting NF kappa B2-p100 processing
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2017, v.491
no.2
, 337-342
SCI
[학술지논문] Prognostic Role of the MicroRNA-200 Family in Various Carcinomas: A Systematic Review and Meta-Analysis
BIOMED RESEARCH INTERNATIONAL, 2017, v.2017
no.1
, 1928021-1928021
[학술지논문] Cancer-Associated Fibroblasts Induce a Collagen Cross-link Switch in Tumor Stroma
MOLECULAR CANCER RESEARCH, 2016, v.14
no.3
, 287-295
SCI
[학술지논문] Exogenous C2 Ceramide Suppresses Matrix Metalloproteinase Gene Expression by Inhibiting ROS Production and MAPK Signaling Pathways in PMA-Stimulated Human Astroglioma Cells
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2016, v.17
no.4
, 477-490
SCIE
[학술지논문] Growth and metastasis of lung adenocarcinoma is potentiated by BMP4-mediated immunosuppression
ONCOIMMUNOLOGY, 2016, v.5
no.11
, 12345670-12345670
SCIE
[학술지논문] Liver X receptor and STAT1 cooperate downstream of Gas6/Mer to induce anti-inflammatory arginase 2 expression in macrophages
SCIENTIFIC REPORTS, 2016, v.6
no.6
, 29673-29688
SCI
[학술지논문] Musashi-2 (MSI2) supports TGF-beta signaling and inhibits claudins to promote non-small cell lung cancer (NSCLC) metastasis
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2016, v.113
no.25
, 6955-6960
SCI
[학술지논문] Necrotic cells influence migration and invasion of glioblastoma via NF-kappa B/AP-1-mediated IL-8 regulation
SCIENTIFIC REPORTS, 2016, v.6
no.1
, 24552-24564
SCIE
[학술지논문] Target sequencing and CR
ISPR/Cas editing reveal simultaneous loss of UTX and UTY in urothelial bladder cancer
ONCOTARGET, 2016, v.7
no.39
, 63252-63260
SCIE
[학술지논문] BMP4 depletion by miR-200 inhibits tumorigenesis and metastasis of lung adenocarcinoma cells
MOLECULAR CANCER, 2015, v.14
no.1
, 173-173
SCIE
[학술지논문] Lysyl hydroxylase 2 induces a collagen cross-link switch in tumor stroma
JOURNAL OF CLINICAL INVESTIGATION, 2015, v.125
no.3
, 1147-1162
SCI
[학술지논문] SHC1 sensitizes cancer cells to the 8-Cl-cAMP treatment
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2015, v.463
no.4
, 673-678
SCI
[학술지논문] Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression
NATURE COMMUNICATIONS, 2014, v.5
no.5241
, 1-12
SCI
[학술발표] Suppression of BMP4 by miR-200 Inhibits Lung Tumorigenesis and MetastasisThe 27th International Conference of the Korean Society for Molecular and Cellular Biology, 대한민국, 서울, 2015-09-22
The 27th International Conference of the Korean Society for Molecular and Cellular Biology, 2015
[학술발표] ZEB1 sensitizes lung adenocarcinoma cells to metastasis suppression by PI3K-targeted therapyThe 41st annual meeting of Korean Cancer Association with Interantional Cancer Conference, 대한민국, 서울, 2015-06-18
The 41st annual meeting of Korean Cancer Association with Interantional Cancer Conference, 2015, 198-199
[학술발표] miR-200 suppresses BMP4 that promotes tumorigenesis and metastasis in lung adenocarcinomaThe 41st Annual Meeting of Korean Cancer Association with International Cancer Conference, 대한민국, 서울, 2015-06-18
The 41st Annual Meeting of Korean Cancer Association with International Cancer Conference, 2015
[학술발표] ZEB1 Sensitizes Lung Cancer Cells to PI3-Kinase-Targeted TherapyThe 26th International Conference of the Korean Society for Molecular and Cellular Biology, 대한민국, 서울, 2014-10-22
The 26th International Conference of the Korean Society for Molecular and Cellular Biology, 2014