이화여자대학교

Jaesang Kim Professor

Life Sciences/Bio-Information Science/Department of Life Science

김재상 프로필 사진 
The research aims of Professor Jaesang Kim includes isolating and functionally characterizing genes involved in development of central nervous system and pathogenesis of lung cancer. He has earned his PhD degree from MIT and published nearly 50 research articles in SCI journals.
  • Director, Ewha Research Center for Systems Biology
  • Science Building C #516
  • 02-3277-3414
  • Office hours
    • 화 10-12시
Research Record
  • Dissecting transcriptome signals of anti-PD-1 response in lung adenocarcinoma Scientific Reports, 2024, v.14 no.1, 21096
    SCIE Scopus dColl.
  • Conserved miR-370-3p/BMP-7 axis regulates the phenotypic change of human vascular smooth muscle cells Scientific reports, 2023, v.13 no.1, 2404
    SCIE Scopus dColl.
  • A Novel Kinase Inhibitor AX-0085 Inhibits Interferon-gamma-Mediated Induction of PD-L1 Expression and Promotes Immune Reaction to Lung Adenocarcinoma Cells CELLS, 2022, v.11 no.1, 19
    SCIE Scopus dColl.
  • Direct cell-to-cell transfer in stressed tumor microenvironment aggravates tumorigenic or metastatic potential in pancreatic cancer npj Genomic Medicine, 2022, v.7 no.1, 63
    SCIE Scopus dColl.
  • Mice transgenic for human CTLA4-CD28 fusion gene show proliferation and transformation of ATLL-like and AITL-like T cells ONCOIMMUNOLOGY, 2022, v.11 no.1, 2015170
    SCIE Scopus dColl.
  • Nox4-IGF2 Axis Promotes Differentiation of Embryoid Body Cells Into Derivatives of the Three Embryonic Germ Layers Stem Cell Reviews and Reports, 2022, v.18 no.3, 1181-1192
    SCIE Scopus dColl.
  • FCN3 functions as a tumor suppressor of lung adenocarcinoma through induction of endoplasmic reticulum stress Cell Death and Disease, 2021, v.12 no.4, 407
    SCIE Scopus dColl.
  • Genome-scale CRISPR screening identifies cell cycle and protein ubiquitination processes as druggable targets for erlotinib-resistant lung cancer Molecular Oncology, 2021, v.15 no.2, 487-502
    SCIE Scopus dColl.
  • iCSDB: An integrated database of CRISPR screens Nucleic Acids Research, 2021 , D956-D961
    SCIE Scopus dColl.
  • Angioimmunoblastic T-cell lymphoma-like lymphadenopathy in mice transgenic for human RHOA with p.Gly17Val mutation ONCOIMMUNOLOGY, 2020, v.9 no.1, 0
    SCIE Scopus dColl.
  • Characterization of TNNC1 as a Novel Tumor Suppressor of Lung Adenocarcinoma Molecules and cells, 2020, v.43 no.7, 619-631
    Scopus dColl.
  • ChimerDB 4.0: an updated and expanded database of fusion genes Nucleic acids research, 2020, v.48 no.D1, D817-D824
    SCIE Scopus dColl.
  • Function of NADPH Oxidases in Diabetic Nephropathy and Development of Nox Inhibitors BIOMOLECULES & THERAPEUTICS, 2020, v.28 no.1, 25-33
    SCIE Scopus KCI dColl.
  • Genome-scale screening of deubiquitinase subfamily identifies USP3 as a stabilizer of Cdc25A regulating cell cycle in cancer CELL DEATH AND DIFFERENTIATION, 2020, v.27 no.11, 3004-3020
    SCIE Scopus dColl.
  • 2-(trimethylammonium)ethyl (R)-3-methoxy-3-oxo-2-stearamidopropyl phosphate enhances thrombopoietin-induced megakaryocytic differentiation and plateletogenesis BMB REPORTS, 2019, v.52 no.7, 434-438
    SCIE Scopus KCI dColl.
  • Identification of tumor suppressor miRNAs by integrative miRNA and mRNA sequencing of matched tumor-normal samples in lung adenocarcinoma MOLECULAR ONCOLOGY, 2019, v.13 no.6, 1356-1368
    SCIE Scopus dColl.
  • Proteogenomic Characterization of Human Early-Onset Gastric Cancer Cancer Cell, 2019, v.35 no.1, 111-1.24E12
    SCIE Scopus dColl.
  • Integrative Profiling of Alternative Splicing Induced by U2AF1 S34F Mutation in Lung Adenocarcinoma Reveals a Mechanistic Link to Mitotic Stress MOLECULES AND CELLS, 2018, v.41 no.8, 733-741
    SCIE Scopus KCI dColl.
  • Isolation and Functional Examination of the Long Non-Coding RNA Redrum Molecules and cells, 2018, v.41 no.2, 134-139
    Scopus dColl.
  • Characterization of developmental defects in the forebrain resulting from hyperactivated mTOR signaling by integrative analysis of transcriptomic and proteomic data SCIENTIFIC REPORTS, 2017, v.7
    SCIE Scopus dColl.
  • Frequent CTLA4-CD28 gene fusion in diverse types of T-cell lymphoma HAEMATOLOGICA, 2016, v.101 no.6, 757-763
    SCIE Scopus dColl.
  • Rapid emergence and mechanisms of resistance by U87 glioblastoma cells to doxorubicin in an in vitro tumor microfluidic ecology PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2016, v.113 no.50, 14283-14288
    SCIE Scopus dColl.
  • Regulation of c-Myc expression by Ahnak promotes induced pluripotent stem cell generation Journal of Biological Chemistry, 2016, v.291 no.2, 752-761
    SCIE Scopus dColl.
  • SoxD transcription factors: Multifaceted players of neural development International Journal of Stem Cells, 2016, v.9 no.1, 3-8
    Scopus dColl.
  • 2-(Trimethylammonium)ethyl (R)-3-methoxy-3-oxo-2-stearamidopropyl phosphate promotes megakaryocytic differentiation of myeloid leukaemia cells and primary human CD34+ haematopoietic stem cells Journal of Tissue Engineering and Regenerative Medicine, 2015, v.9 no.4, 435-446
    SCIE Scopus dColl.
  • A highly recurrent novel missense mutation in CD28 among angioimmunoblastic T-cell lymphoma patients Haematologica, 2015, v.100 no.12, e505-e507
    SCIE Scopus dColl.
  • Characterization of SLC22A18 as a tumor suppressor and novel biomarker in colorectal cancer Oncotarget, 2015, v.6 no.28, 25368-25380
    SCIE Scopus dColl.
  • Cytosolic Hsp60 orchestrates the survival and inflammatory responses of vascular smooth muscle cells in injured aortic vessels Cardiovascular Research, 2015, v.106 no.3, 498-508
    SCIE Scopus dColl.
  • Hairy and Enhancer of Split 6 (Hes6) Deficiency in Mouse Impairs Neuroblast Differentiation in Dentate Gyrus Without Affecting Cell Proliferation and Integration into Mature Neurons Cellular and Molecular Neurobiology, 2015, 24 Jun 2015
    SCIE Scopus dColl.
  • NEDD4 controls intestinal stem cell homeostasis by regulating the Hippo signalling pathway NATURE COMMUNICATIONS, 2015, v.6
    SCIE Scopus dColl.
  • Phytosphingosine promotes megakaryocytic differentiation of myeloid leukemia cells BMB Reports, 2015, v.48 no.12, 691-695
    SCIE KCI Scopus dColl.
  • VAMP2-NRG1 Fusion Gene is a Novel Oncogenic Driver of Non-Small-Cell Lung Adenocarcinoma JOURNAL OF THORACIC ONCOLOGY, 2015, v.10 no.7, 1107-1111
    SCIE Scopus dColl.
  • VAMP2-NRG1 fusion gene is a novel oncogenic driver of non-small cell lung adenocarcinoma CANCER RESEARCH, 2015, v.75
    SCIE Scopus dColl.
  • 2-(Trimethylammonium) Ethyl (R)-3-Methoxy-3-oxo-2-Stearamidopropyl Phosphate Suppresses Osteoclast Maturation and Bone Resorption by Targeting Macrophage-Colony Stimulating Factor Signaling MOLECULES AND CELLS, 2014, v.37 no.8, 628-635
    SCIE KCI Scopus dColl.
  • A recurrent inactivating mutation in RHOA GTPase in angioimmunoblastic T cell lymphoma NATURE GENETICS, 2014, v.46 no.4, 371-
    SCIE Scopus dColl.
  • Ahnak functions as a tumor suppressor via modulation of TGF beta/Smad signaling pathway ONCOGENE, 2014, v.33 no.38, 4675-4684
    SCIE Scopus dColl.
  • Down-regulation of Sox11 is required for efficient osteogenic differentiation of adipose-derived stem cells Molecules and Cells, 2014, v.37 no.4, 337-344
    Scopus dColl.
  • Exome and transcriptome profiling of lung adenocarcinoma in female never-smokers CANCER RESEARCH, 2014, v.74 no.19
    SCIE Scopus dColl.
  • Gene Expression Regulation by Agonist-Independent Constitutive Signaling of Melanocortin-1 Receptor Endocrinology and Metabolism, 2014, 제29권 2호, 179-184
    KCI dColl.
  • Gene expression regulation by agonist-independent constitutive signaling of Melanocortin-1 receptor Endocrinology and Metabolism, 2014, v.29 no.2, 179-184
    Scopus KCI dColl.
  • Nox4-Mediated Cell Signaling Regulates Differentiation and Survival of Neural Crest Stem Cells MOLECULES AND CELLS, 2014, v.37 no.12, 907-911
    SCIE KCI Scopus dColl.
  • Positive feedback loop between Sox2 and Sox6 inhibits neuronal differentiation in the developing central nervous system PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2014, v.111 no.7, 2794-2799
    SCIE Scopus dColl.
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Courses

  • 2025-2nd

    • General Biology

      • Subject No 20412Class No 01
      • 1Year ( 3Credit , 3Hour) Wed 3~3 (SCI-AA) , Fri 2~2 (102)
        • Syllabus(File)

    • Molecular Biology Ⅰ

      • Subject No 20600Class No 03
      • 2Year ( 3Credit , 3Hour) Mon 3~3 (POSCO365) , Wed 2~2 (POSCO365)
        • Syllabus(File)

    • Life Science Seminar Ⅳ

      • Subject No G16931Class No 01
      • Year ( 3Credit , 3Hour) Thu 3~4 (SCI-C)
        • Syllabus(File)

    • Special Topics in Advanced Biochemistry Ⅱ

      • Subject No G16949Class No 01
      • Year ( 3Credit , 3Hour) Thu 5~6 (SCI-C)
        • Syllabus(File)

    • Regulation of Gene Manifestation

      • Subject No G16996Class No 01
      • Year ( 3Credit , 3Hour) Tue 5~6 (SCI-C)
        • Syllabus(File)

  • 2025-1st

    • General Biology Ⅰ

      • Subject No 20413Class No 01
      • 1Year ( 3Credit , 3Hour) Mon 2~2 (POSCO453) , Thu 3~3 (POSCO453)
        • Syllabus(File)

    • General Biology : Laboratory Work Ⅰ

      • Subject No 33332Class No 01
      • 1Year ( 1Credit , 1.5Hour) Mon 6~6 (SCI-AA203)
        • Syllabus(File)

    • General Biology : Laboratory Work Ⅰ

      • Subject No 33332Class No 02
      • 1Year ( 1Credit , 1.5Hour) Wed 5~5 (SCI-AA203)
        • Syllabus(File)

    • Molecular Biology Ⅱ

      • Subject No 35825Class No 01
      • 3Year ( 3Credit , 3Hour) Mon 5~5 (POSCO361) , Wed 4~4 (POSCO361)
        • Syllabus(File)

    • Colloquium of Life Science Research

      • Subject No 36337Class No 01
      • 3Year ( 3Credit , 3Hour) Tue 4~4 (POSCO452) , Fri 5~5 (POSCO452)
        • Syllabus(File)

    • Understanding the Mechanism of Future Disease

      • Subject No G16972Class No 01
      • Year ( 3Credit , 3Hour) Mon 3~4 (SCI-C)
        • Syllabus(File)

    • Advanced Molecular Biology

      • Subject No G16977Class No 01
      • Year ( 3Credit , 3Hour) Wed 6~7 (SCI-C)
        • Syllabus(File)

  • 2024-2nd

    • Molecular Biology Ⅰ

      • Subject No 20600Class No 03
      • 2Year ( 3Credit , 3Hour) Mon 3~3 (POSCO366) , Wed 2~2 (POSCO366)
        • Syllabus(File)

    • Life Science Seminar Ⅱ

      • Subject No G16929Class No 01
      • Year ( 3Credit , 3Hour) Thu 3~4 (SCI-C-)
        • Syllabus(File)

    • Special Topics in Advanced Biochemistry Ⅱ

      • Subject No G16949Class No 01
      • Year ( 3Credit , 3Hour) Thu 5~6 (SCI-C)
        • Syllabus(File)

    • Regulation of Gene Manifestation

      • Subject No G16996Class No 01
      • Year ( 3Credit , 3Hour) Tue 5~6 (SCI-C)
        • Syllabus(File)

  • 2024-1st

    • General Biology

      • Subject No 20412Class No 03
      • 1Year ( 3Credit , 3Hour) Mon 3~3 (POSCO453) , Wed 2~2 (POSCO453)
        • Syllabus(File)

    • General Biology: Laboratory Work Ⅰ

      • Subject No 33332Class No 01
      • 1Year ( 1Credit , 1.5Hour) Mon 6~6 (SCI-AA203)
        • Syllabus(File)

    • General Biology: Laboratory Work Ⅰ

      • Subject No 33332Class No 02
      • 1Year ( 1Credit , 1.5Hour) Wed 6~6 (SCI-AA203)
        • Syllabus(File)

    • Molecular Biology Ⅱ

      • Subject No 35825Class No 03
      • 3Year ( 3Credit , 3Hour) Wed 3~3 (POSCO465) , Fri 2~2 (POSCO465)
        • Syllabus(File)

    • Special Topics in Advanced Biochemistry Ⅰ

      • Subject No G16948Class No 01
      • Year ( 3Credit , 3Hour) Mon 3~4 (SCI-C418)
        • Syllabus(File)

    • Advanced Molecular Biology

      • Subject No G16977Class No 01
      • Year ( 3Credit , 3Hour) Wed 5~6 (SCI-C)
        • Syllabus(File)

  • 2023-2nd

  • 2023-1st

  • 2022-2nd

    • General Biology

      • Subject No 20412Class No 04
      • 1Year ( 3Credit , 3Hour) Mon 3~3 (POSCO365) , Wed 2~2 (POSCO365)
        • Syllabus(File)

    • Molecular Biology I

      • Subject No 20600Class No 02
      • 2Year ( 3Credit , 3Hour) Mon 2~2 (POSCO366) , Thu 3~3 (POSCO366)
        • Syllabus(File)

    • Advanced Experiments in Life Sciences Capstone Design II

      • Subject No 35830Class No 01
      • 4Year ( 2Credit , 3Hour) Sat 1~2 (SCI-AA205)
        • Syllabus(File)

    • Special Topics in Advanced BiochemistryⅡ

      • Subject No G16949Class No 01
      • Year ( 3Credit , 3Hour) Wed 6~7 (SCI-C)
        • Syllabus(File)

    • Regulation of Gene Manifestation

      • Subject No G16996Class No 01
      • Year ( 3Credit , 3Hour) Tue 5~6 (SCI-C)
        • Syllabus(File)

  • 2022-1st

    • General Biology I

      • Subject No 20413Class No 05
      • 1Year ( 3Credit , 3Hour) Tue 4~4 (POSCO365) , Fri 5~5 (POSCO365)
        • Syllabus(File)

    • Molecular Biology II

      • Subject No 35825Class No 02
      • 3Year ( 3Credit , 3Hour) Tue 5~5 (POSCO362) , Thu 6~6 (POSCO362)
        • Syllabus(File)

    • Colloquium of Life Science Research

      • Subject No 36337Class No 01
      • 3Year ( 3Credit , 3Hour) Mon 3~3 (SCI-AA) , Wed 2~2 (101)
        • Syllabus(File)

    • Special Topics in Advanced BiochemistryⅠ

      • Subject No G16948Class No 01
      • Year ( 3Credit , 3Hour) Mon 3~4 (-)
        • Syllabus(File)

    • Advanced Molecular Biology

      • Subject No G16977Class No 01
      • Year ( 3Credit , 3Hour) Tue 5~6 (SCI-C)
        • Syllabus(File)
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Academic Background

Massachusetts Institute of Technology Ph.D.(Biology)