Nutritional Pathophysiology Lab is trying to find molecular changes in differnet disease states and to determine the molecular targets that may cause the critical changes of disease progress or even prevention of the onset of the diseases especially in liver.
Department Chair, Nutritional Science & Food Management/Director, Global Food and Nutrition Research Institute
Inhibitory Effects of Wheat Sprouts Extract on RANKL-Induced Osteoclast Differentiation via Suppressing MAPK and NFATc1 Signaling PathwaysJournal of Medicinal Food, 2023, v.26 no.7, 480-488
Association between Use of Nutrition Labels and Risk of Chronic Kidney Disease: The Korean National Health and Nutrition Examination Survey (KNHANES) 2008–2019Nutrients, 2022, v.14 no.9, 1731
The Relationship between Prohibitin 1 Expression, Hepatotoxicity Induced by Acetaminophen, and Hepatoprotection by S-Adenosylmethionine in AML12 CellsJournal of Microbiology and Biotechnology, 2022, v.32 no.11, 1447-1453
Development of a Human Estrogen Receptor Dimerization Assay for the Estrogenic Endocrine-Disrupting Chemicals Using Bioluminescence Resonance Energy TransferINTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 2021, v.18 no.16, 8875
Analysis and management of abnormal cases by multiple intake of Korean health functional foodsJournal of the Korean Society of Food Science and Nutrition, 2020, v.49 no.5, 511-520
Lipopolysaccharide-induced innate immune responses are exacerbated by Prohibitin 1 deficiency and mitigated by S-adenosylmethionine in murine macrophagesPLOS ONE, 2020, v.15 no.11, e0241224
Long-Term Feeding of Soy Protein Attenuates Choline Deficient-Induced Adverse Effects in Wild Type Mice and Prohibitin 1 Deficient Mice Response More Sensitively.Preventive Nutrition and Food Science, 2019, v.24 no.1, 32~40
Long-term feeding of soy protein attenuates choline deficient-induced adverse effects in wild type mice and prohibitin 1 deficient mice response more sensitivelyPreventive Nutrition and Food Science, 2019, v.24 no.1, 32-40
Analysis of consumption status of calcium with related factors in a Korean population: Based on data from the 2013∼2015 Korean National Health and Nutritional Examination Survey (KNHANES)Journal of the Korean Society of Food Science and Nutrition, 2018, v.47 no.3, 328-336
Antioxidative and Anti-Inflammatory Activities of Akebia quinata Extracts in an In Vitro Model of Acute Alcohol-Induced HepatotoxicityJOURNAL OF MEDICINAL FOOD, 2017, v.20 no.9, 912-922
Cellular Antioxidant and Anti-Inflammatory Effects of Coffee Extracts with Different Roasting LevelsJournal of Medicinal Food, 2017, v.20 no.6, 626-635
Effects of Morphological Characteristics of Muscle Fibers on Porcine Growth Performance and Pork QualityKOREAN JOURNAL FOR FOOD SCIENCE OF ANIMAL RESOURCES, 2016, v.36 no.5, 583-593
Effects of S-Adenosylmethionine and Its Combinations With Taurine and/or Betaine on Glutathione Homeostasis in Ethanol-induced Acute Hepatotoxicity대한암예방학회지, 2016, v.21 no.3, 164~172
Effects of extract of lactic acid bacteria culture media on quality characteristics of pork loin and antimicrobial activity against pathogenic bacteria during cold storageJournal of the Korean Society of Food Science and Nutrition, 2016, v.45 no.10, 1476-1480
Effects of oleanolic acid and hederagenin on acute alcohol-induced hepatotoxicity in miceJournal of the Korean Society of Food Science and Nutrition, 2016, v.45 no.3, 307-312
Protective Effects of S-Adenosylmethionine and Its Combinations With Taurine and/or Betaine Against Lipopolysaccharide or Polyinosinic-polycytidylic Acid-induced Acute Hepatotoxicity대한암예방학회지, 2016, v.21 no.3, 152~163
Relationship between Broca index of late school-aged children and their mothers’ eating, cooking, and exercise habitJournal of the Korean Society of Food Science and Nutrition, 2016, v.45 no.10, 1488-1496
Effects of various garlic (Allium sativum) extracts on cholesterol synthesis in HepG2 cellsJournal of the Korean Society of Food Science and Nutrition, 2015, v.44 no.12, 1779-1784
Protective effects of Akebia quinata fruit extract on acute alcohol-induced hepatotoxicity in miceKorean Journal of Food Science and Technology, 2014, v.46 no.5, 622-629
[학술지논문] Associations of Food Insecurity with Dietary Inflammatory Potential and Risk of Low Muscle Strength
NUTRIENTS, 2023, v.15
no.5
, 1-14
SCIE
[학술지논문] Inhibitory Effects of Wheat Sprouts Extract on RANKL-Induced Osteoclast Differentiation via Suppressing MAPK and NFATc1 Signaling Pathways
JOURNAL OF MEDICINAL FOOD, 2023, v.26
no.7
, 480-488
SCIE
[학술지논문] Organoid Establishment of Long-Term Culture Using Primary Mouse Hepatocytes and Evaluation of Liver Function
Preventive Nutrition and Food Science, 2023, v.28
no.3
, 360-369
Scopus
[학술지논문] Association between Use of Nutrition Labels and Risk of Chronic Kidney Disease: The Korean National Health and Nutrition Examination Survey (KNHANES) 2008-2019
NUTRIENTS, 2022, v.14
no.9
, 1731-1731
SCIE
[학술지논문] Effects of Amino Acids Supplementation on Lipid and Glucose Metabolism in HepG2 Cells
NUTRIENTS, 2022, v.14
no.15
, 1-13
SCIE
[학술지논문] Saturated Fatty Acid-Induced Impairment of Hepatic Lipid Metabolism Is Worsened by Prohibitin 1 Deficiency in Hepatocytes
JOURNAL OF MEDICINAL FOOD, 2022, v.25
no.8
, 845-852
SCI
[학술지논문] The Relationship between Prohibitin 1 Expression, Hepatotoxicity Induced by Acetaminophen, and Hepatoprotection by S-Adenosylmethionine in AML12 Cells
Journal of Microbiology and Biotechnology, 2022, v.32
no.11
, 1447-1453
[학술지논문] Development of a Human Estrogen Receptor Dimerization Assay for the Estrogenic Endocrine-Disrupting Chemicals Using Bioluminescence Resonance Energy Transfer
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 2021, v.18
no.16
, 1-13
SSCI
[학술지논문] We Are Not Informed Enough
Food Supplements and Biomaterials for Health, 2021, v.1
no.4
, 1-2
[학술지논문] Lipopolysaccharide-induced innate immune responses are exacerbated by Prohibitin 1 deficiency and mitigated by S-adenosylmethionine in murine macrophages
PLOS ONE, 2020, v.15
no.11
, 0241224-0241224
SCIE
[학술지논문] Analysis and management of abnormal cases by multiple intake of Korean health functional foods
Journal of the Korean Society of Food Science and Nutrition, 2020, v.49
no.5
, 511-520
Scopus
[학술지논문] Long-term feeding of soy protein attenuates choline deficient-induced adverse effects in wild type mice and prohibitin 1 deficient mice response more sensitively
Preventive Nutrition and Food Science, 2019, v.24
no.1
, 32-40
Scopus
[학술지논문] Analysis of consumption status of calcium with related factors in a Korean population: Based on data from the 2013∼2015 Korean National Health and Nutritional Examination Survey (KNHANES)
Journal of the Korean Society of Food Science and Nutrition, 2018, v.47
no.3
, 328-336
Scopus
[학술지논문] Effects of Coffee Extracts with Different Roasting Degrees on Antioxidant and Anti-Inflammatory Systems in Mice
NUTRIENTS, 2018, v.10
no.3
, 1-13
SCIE
[학술지논문] Design and Implementation of a Health Data Collection Mobile Platform for Personalized Health Diagnosis
데이타베이스연구, 2018, v.34
no.1
, 59-68
KCI
[학술지논문] 대사증후군 예방을 위한 모바일 헬스 애플리케이션의 개인맞춤형 콘텐츠 개발
보건교육건강증진학회지, 2018, v.35
no.3
, 25-40
KCI
[학술지논문] Antioxidative and Anti-Inflammatory Activities of Akebia quinata Extracts in an In Vitro Model of Acute Alcohol-Induced Hepatotoxicity
JOURNAL OF MEDICINAL FOOD, 2017, v.20
no.9
, 912-922
SCI
[학술지논문] Cellular Antioxidant and Anti-Inflammatory Effects of Coffee Extracts with Different Roasting Levels
JOURNAL OF MEDICINAL FOOD, 2017, v.20
no.6
, 626-635
SCI
[학술지논문] 성인의 만성질환 관련 건강위험행태요인 군집현상 분석
보건교육건강증진학회지, 2017, v.34
no.3
, 21-31
KCI
[학술지논문] Dietary beet pulp decreases taurine status in dogs fed low protein diet
한국동물자원과학회지, 2016, v.58
no.8
, 1-10
KCI
[학술지논문] Effect of beverage containing fermented akebia quinata extracts on alcoholic hangover
Preventive Nutrition and Food Science, 2016, v.21
no.1
, 9-13
Scopus
[학술지논문] Effects of Morphological Characteristics of Muscle Fibers on Porcine Growth Performance and Pork Quality
KOREAN JOURNAL FOR FOOD SCIENCE OF ANIMAL RESOURCES(한국축산식품학회지), 2016, v.36
no.5
, 583-593
SCIE
[학술지논문] Effects of S-Adenosylmethionine and Its Combinations With Taurine and/or Betaine on Glutathione Homeostasis in Ethanol-induced Acute Hepatotoxicity
대한암예방학회지, 2016, v.21
no.3
, 164-172
KCI
[학술지논문] Effects of extract of lactic acid bacteria culture media on quality characteristics of pork loin and antimicrobial activity against pathogenic bacteria during cold storage
JOURNAL OF THE KOREAN SOCIETY OF FOOD SCIENCE AND NUTRITION(한국식품영양과학회지), 2016, v.45
no.10
, 1476-1480
Scopus
[학술지논문] Prohibitin 1 Regulates the H19-Igf2 Axis and Proliferation in Hepatocytes
JOURNAL OF BIOLOGICAL CHEMISTRY, 2016, v.291
no.46
, 24148-24159
SCI
[학술지논문] Protective Effects of S-Adenosylmethionine and Its Combinations With Taurine and/or Betaine Against Lipopolysaccharide or Polyinosinic-polycytidylic Acid-induced Acute Hepatotoxicity
대한암예방학회지, 2016, v.21
no.3
, 152-163
KCI
[학술지논문] Relationship between Broca index of late school-aged children and their mothers’ eating, cooking, and exercise habit
JOURNAL OF THE KOREAN SOCIETY OF FOOD SCIENCE AND NUTRITION(한국식품영양과학회지), 2016, v.45
no.10
, 1488-1496
Scopus
[학술지논문] Effects of oleanolic acid and hederagenin on acute alcohol-induced hepatotoxicity in mice
Journal of the Korean Society of Food Science and Nutrition, 2016, v.45
no.3
, 307-312
Scopus
[학술지논문] Effects of various garlic (Allium sativum) extracts on cholesterol synthesis in HepG2 cells
JOURNAL OF THE KOREAN SOCIETY OF FOOD SCIENCE AND NUTRITION(한국식품영양과학회지), 2015, v.44
no.12
, 1779-1784
Scopus
[학술지논문] Interactions between Myc and Mediators of Inflammation in Chronic Liver Diseases
MEDIATORS OF INFLAMMATION, 2015, v.2015
no.276850
, 1-12
SCI
[학술지논문] Molecular mechanisms of lipopolysaccharide-mediated inhibition of glutathione synthesis in mice
FREE RADICAL BIOLOGY AND MEDICINE, 2014, v.68
no.0
, 148-158
SCI
[학술지논문] 급성 알코올 간독성을 유발한 생쥐에 있어서 으름 열매 추출물의 간 기능 보호효과
KOREAN JOURNAL OF FOOD SCIENCE AND TECHNOLOGY(한국식품과학회지), 2014, v.46
no.5
, 622-629
Scopus
[학술지논문] A Survey for Needs and Preference of Food and Nutrition information on Mass Media for Korean Female Adults
대한지역사회영양학회지, 2014, v.19
no.6
, 550-557
KCI
[학술지논문] Animal models of cholangiocarcinoma
CURRENT OPINION IN GASTROENTEROLOGY, 2013, v.29
no.3
, 312-318
SCI
[학술지논문] MicroRNAs regulate methionine adenosyltransferase 1A expression in hepatocellular carcinoma
JOURNAL OF CLINICAL INVESTIGATION, 2013, v.123
no.1
, 285-298
SCI
[학술지논문] Protective Effects of Guava Pulp on Cholestatic Liver Injury
ISRN Hepatology, 2013, v.2013
no.601071
, 1-11
[학술지논문] Mechanism and Significance of Changes in Glutamate-Cysteine Ligase Expression during Hepatic Fibrogenesis
JOURNAL OF BIOLOGICAL CHEMISTRY, 2012, v.287
no.43
, 36341-36355
SCI
[학술지논문] Recent advances of miRNA involvement in hepatocellular carcinoma and cholangiocarcinoma
Open Journal of Internal Medicine, 2012, v.2
no.3
, 135-162
[학술지논문] Hepatoprotective Functions of Sulfur Containing Amino Acids: Possibilities of Hepatocellular Carcinoma Prevention
한국식품과학회지, 2012, v.44
no.6
, 653-657
[저역서] 2020 Dietary Reference Intakes for Koreans
보건복지부, 2020, 274
[저역서] 2015 Dietary Reference Intakes for Koreans
보건복지부, 2015, 1118
[학술발표] A Study on the Proposal for Convergence Health Functional Food Management System2023 KoSFOST International Symposium and Annual Meeting, 대한민국, 서귀포시, 2023-06-30
Sustainable Food Innovation: A Bridge to the Future for All, 2023, 836-836
[학술발표] Discovery of Biomarkers for the Diagnosis of Liver Disease Susceptibility by Omics Analysis in Liver Specific Prohibitin 1 Deficient Mice2023 한국대사체학회 정기학술대회, 대한민국, 서울, 2023-04-07
2023 한국대사체학회 정기학술대회 및 제11차 정기총, 2023, 96-96
[학술발표] Discovery of biomarkers for the diagnosis of liver disease susceptibility by metabolome analysis in liver specific Phb1 deficient mice2023 KFN International Symposium and Annual Meeting, 대한민국, 부산, 2023-10-18
Sustainable Food System for a Healthy & Value-Oriented Life, 2023, 518-518
[학술발표] Novel Effects of Prohibitin 1 Expression Level on Cholesterol and Lipid Homeostasis2023 KFN International Symposium and Annual Meeting, 대한민국, 부산, 2023-10-18
Sustainable Food System for a Healthy & Value-Oriented Life, 2023, 518-518
[학술발표] The Impact of the Expression Level of Prohibitin 1 on the Cholesterol MetabolismNutrition 2023, 미국, Boston, 2023-07-24
Nutrition 2023, 2023
[학술발표] Diversification of health functional food through birth of convergence health functional food and deregulation2023 한국영양학회 추계국제학술대회, 대한민국, 서울, 2023-10-13
Understanding Metabolism: Scientific ADvances and Practical Applications, 2023, 46-47
[학술발표] Hepatic Damage Sensitivity of Prohibitin 1 Deficient Mice and Relieving Effects of S-Adenosylmethionine2022년도 제42회 한국운동영양학회 춘계학술대회, 대한민국, 서울, 2022-05-20
New Paradigms of Nutrition and Exercise to Improve Health and Sports Performance in the New Normal Era , 2022, 57-72
[학술발표] Organoid Establishment for Long-Term Culture using Primary Mouse Hepatocytes and Evaluation of Liver Function as a Health Functional Food Test Model2022 KFN International Symposium and Annual Meeting, 대한민국, 서귀포시, 2022-10-21
New Frontiers for Green Biotechnology in Food Science and Nutrition, 2022, 380-380
[학술발표] Prohibitin 1 affects cell cycle signaling associated with hydrogen peroxide oxidative stress2022 KFN International Symposium and Annual Meeting, 대한민국, 서귀포시, 2022-10-21
New Frontiers for Green Biotechnology in Food Science and Nutrition, 2022, 628-628
[학술발표] 한국형 건강기능식품 섭취 실태조사를 통한 한국 성인의 건강기능식 품으로부터의 영양·기능성분 섭취량 추정2022 KFN International Symposium and Annual Meeting, 대한민국, 서귀포시, 2022-10-21
New Frontiers for Green Biotechnology in Food Science and Nutrition , 2022, 543-543
[학술발표] Development for early diagnosis of liver disease using metabolite changes in liver-specific Phb1 deficient mice2021 KFN International Symposium and Annual Meeting, 대한민국, 부산, 2021-10-29
Tailored to Fit: Food & Nutrition in New Era, 2021
[학술발표] Prohibitin 1 can protect hepatocytes against Acetaminophen toxicity in AML 12 cells2020 KFN International Symposium and Annual Meeting, 대한민국, 서귀포시, 2020-10-23
Health Aging & Sustainable Life, 2020, 218-219
[학술발표] Analysis of abnormal cases by multiple intake of health functional foods2019 KFN International Symposium and Annual Meeting, 대한민국, 서귀포시, 2019-10-23
The 4th Industrial Revolution: The ROle of Food & Nutritional Sciences, 2019, 232-232
[학술발표] BRET (Bioluminescence Resonance Energy Transfer)-based Androgen Binding Asay Detection Androgenic CHemical Compounds in Foods and Related Materials2019 KFN International Symposium and Annual Meeting, 대한민국, 서귀포시, 2019-10-25
The 4th Industrial Revolution: The Role of Food & Nutritional Sciences, 2019, 435-436
[학술발표] Effects of Branched Chain Amino Acids Supplementation on Lipid and Glucose Metabolism in HepG2 Cells2019 KFN International Symposium and Annual Meeting, 대한민국, 서귀포시, 2019-10-24
The 4th Industrial Revolution: The Role of Food & Nutritional Sciences, 2019, 364-365
[학술발표] Power of Sulfur Containing Amino Acids: in Liver한국독성학회 2019 제35차 정기학술대회, 대한민국, 서귀포시, 2019-11-04
Bridging Modern Toxicology to DIsease Prevention, 2019
[학술발표] Prohibitin 1 deficiency causes impairment of lipid metabolism and the disruption is deteriorated by excessive palmitic acids in hepatocytesNutrition 2019, 미국, Baltimore, 2019-06-10
Nutrition 2019, 2019
[학술발표] Depletion of Prohibitin 1 Maintains Low Glutathione Level Despite Treatment of S-Adenosylmethionine and Its Combination with Taurine and/or BetaineNutrition 2018, 미국, Boston, 2018-06-11
Where the Best in Science & Health Meet, 2018
[학술발표] Immunity and Amino AcidsThe 19th Congress of PENSA 2018, 대한민국, 서울, 2018-06-16
Innovative Nutrition in GLobal Health, 2018, 49-49
[학술발표] Modulation of the LPS-Induced Inflammatory Responses by Prohibitin 1 and S-Adenosylmethionine in RAW 264.7 Cells2018 KFN International Symposium and Annual Meeting, 대한민국, 부산, 2018-11-01
Food, Nutrition and Health: Human Microbiome, 2018, 494-494
[학술발표] Modulation of the LPS-induced inflammatory responses by prohibitin 1 in RAW 264.7 cells2018 KoSFoST International Symposium and Annual Meeting, 대한민국, 부산, 2018-06-29
KoSFoST Beyond 50 Years: Review the New in Food Science, 2018, 680-680
[학술발표] Food and Nutrition at 4.0 Generation2017 KFN International Symposium and Annual Meeting, 대한민국, 경주, 2017-11-09
Tranlational Food & Nutrition Research for Healthy Life, 2017, 108-108
[학술발표] Changing anti-inflammatory effects of coffee extracts with different levels of roastingKoSFoST International Symposium and Annual Meeting, 대한민국, 제주, 2017-06-23
The role of food scientists & food industries for food security, 2017, 520-520
[학술발표] Cellular antioxidant effects of coffee extracts with different roasting degrees2016 KOSFOST International Symposium and Annual Meeting, 대한민국, 대구, 2016-08-18
Food Science for Daily Living via Innovation and Convergence, 2016, 53-53
[학술발표] Hepato-Protective effects of sulfur containing amino acids mixtures against anti-bacterial or anti-viral challenges2016년 한국노인과학학술대회, 대한민국, 서울, 2016-11-25
초고령사히 대응 고령친화환경 전략, 2016, 474-475
[학술발표] Antibacterial Effectts of the Culture Supplement of Selected Lactobacilli Strains2015 KFN International Symposium and Annual Meeting, 대한민국, Pyeongchang, 2015-08-24
Phytonutrients and Healthy Foods, 2015
[학술발표] Correlation between prohibitin1 gene expression and susceptibility of liver disease through human liver tissue analysis 20th International Conference on Annual Meeting of Korean Society of Cancer Prevention, 대한민국, 서울, 2015-12-10
20th International Conference on Annual Meeting of Korean Society of Cancer Prevention, 2015, 94-94
[학술발표] Effects of garlin (Allium sativum) extracts on cellular choleterol synthesis of HepG2 with different extraction method2015 한국영양학회 추계학술대회 및 제50차 정기총회, 대한민국, 서울, 2015-11-06
Nutrition and Omics: CHallenges and Breakthrough, 2015
[학술발표] Extract of Mammea lonifolia Planch and Triana Fruit Induces APoptosis in Human Colon Cancer by a Mitochondria Pathway2015 KFN International Symposium and Annual Meeting, 대한민국, Pyeongchang, 2015-08-24
Phytonutrients and Healthy Foods, 2015
[학술발표] Possibility of cancer prevention of Prohibitin1UKC2015, 미국, Atlanta, 2015-07-30
UKC2015 Conference Proceedings, 2015
[학술발표] Possibilty of cancer prevention of prohibitin12015 한국영양학회 추계학술대회 및 제50차 정기총회, 대한민국, 서울, 2015-11-06
Nutrition and Omics: Challenges and Breakingthrough, 2015, 148-156
[학술발표] Amino Acids Fight to Sarcopenia2014년 2차 근감소증 심포지엄, 대한민국, 서울, 2014-01-25
대한근감소증연구회 2014년 2차 근감소증 심포지엄, 2014, 71-75
[학술발표] Developing an Integrated Multi-Disciplinary Healthcare Application for Elderly Disease Management2014 Fifth International Conference on Information Science and Application, 대한민국, 서울, 2014-06-06
ICISA 2014, 2014, 600-601
[학술발표] Effect of Extract of Lactic Acid Bacteria Culture
Media on Quality Characteristics of Pork Loin and Antimicrobial Activity of Listeria monocytogenes during Cold Storage 2014 한국식품과학회 제81차 학술대회 및 정기총회, 대한민국, 광주, 2014-08-26
2014 Annual Meeting of KOSFOST: Creative Food Science for the future, 2014, 401-401
[학술발표] Extract of Akebia quinata has a therapeutic role as anti-inflammatory and antioxidant in alcohol injury mouse hepatocyte2014 International Symposium and Annual Meeting of KFN, 대한민국, 대전, 2014-10-29
2014 International Symposium and Annual: Lifelong Health and Welness from Nutrition and Food, 2014, 399-399
[학술발표] Prohibitin1 regulates H19 and insulin-like growth factor 2 expression in hepatocytes and liverExperimental Biology 2014, 미국, San Doego, 2014-04-28
EB2014, 2014, 71-71
[학술발표] Tumor Suppressor Function of Prohibitin1 through Regulating Insulin-like Growth Factor II mRNA-binding Protein3 Osaek Symposium, 대한민국, 강원도, 2014-07-04
Osaek Symposium, 2014, 19-19
[학술발표] A new candidate helper for healthy liver, Prohibitin12013 한국식품과학회 Annual Meeting, 대한민국, 천안, 2013-08-28
Innovations in Food Science for Human Well-Being, 2013, 33-33
[학술발표] Effects of Akebia Quinata extracts with antioxidants activity and hepatoprotective function on mouse liver2013 한국영양학회 추계학술대회, 대한민국, 서울, 2013-11-08
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[학술발표] Prohibitin1, Re-visit as a tumor-suppressor of liver cancerCanada-Korea Conference, 캐나다, Whistler, 2012-08-07
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