Research Record

• AZD7648, a DNA-PKcs inhibitor, overcomes radioresistance in Hep3B xenografts and cells under tumor hypoxia AMERICAN JOURNAL OF CANCER RESEARCH, 2023, v.13 no.10, 4918-4930
  SCIE Scopus dColl.
• Kidney protective potential of lactoferrin: pharmacological insights and therapeutic advances Korean Journal of Physiology and Pharmacology, 2022, v.26 no.1, 1-13
  SCIE Scopus KCI dColl.
• Pan-Src kinase inhibitor treatment attenuates diabetic kidney injury via inhibition of Fyn kinase-mediated endoplasmic reticulum stress EXPERIMENTAL AND MOLECULAR MEDICINE, 2022, v.54 no.8, 1086-1097
  SCIE Scopus KCI dColl.
• Peroxisomal Fitness: A Potential Protective Mechanism of Fenofibrate against High Fat Diet-Induced Non- Alcoholic Fatty Liver Disease in Mice DIABETES & METABOLISM JOURNAL, 2022, v.46 no.6, 829-842
  SCIE Scopus KCI dColl.
• Activation of beta(2) adrenergic receptor signaling modulates inflammation: a target limiting the progression of kidney diseases ARCHIVES OF PHARMACAL RESEARCH, 2021, v.44 no.1, 49-62
  SCIE Scopus KCI dColl.
• Associations of Circulating Irisin with FNDC5 Expression in Fat and Muscle in Type 1 and Type 2 Diabetic Mice BIOMOLECULES, 2021, v.11 no.2, 322
  SCIE Scopus dColl.
• CO-Releasing Molecule-2 Prevents Acute Kidney Injury through Suppression of ROS-Fyn-ER Stress Signaling in Mouse Model OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2021, v.2021, 9947772
  SCIE Scopus dColl.
• Dojuksan ameliorates tubulointerstitial fibrosis through irisin-mediated muscle-kidney crosstalk PHYTOMEDICINE, 2021, v.80, 153393
  SCIE Scopus dColl.
• Dual actions of a2a and a3 adenosine receptor ligand prevents obstruction-induced kidney fibrosis in mice International Journal of Molecular Sciences, 2021, v.22 no.11, 5667
  SCIE Scopus dColl.
• Exercise-Induced Irisin Decreases Inflammation and Improves NAFLD by Competitive Binding with MD2 CELLS, 2021, v.10 no.12, 3306
  SCIE Scopus dColl.
• Fumarate modulates phospholipase A2 receptor autoimmunity-induced podocyte injury in membranous nephropathy Kidney International, 2021, v.99 no.2, 443-455
  SCIE Scopus dColl.
• Heukcha, naturally post-fermented green tea extract, ameliorates diet-induced hypercholesterolemia and NAFLD in hamster JOURNAL OF FOOD SCIENCE, 2021, v.86 no.11, 5016-5025
  SCIE Scopus dColl.
• KF-1607, a novel pan src kinase inhibitor, attenuates obstruction-induced tubulointerstitial fibrosis in mice Biomolecules and Therapeutics, 2021, v.29 no.1, 41-51
  SCIE Scopus KCI dColl.
• Pharmacotherapy against oxidative stress in chronic kidney disease: Promising small molecule natural products targeting nrf2-ho-1 signaling Antioxidants, 2021, v.10 no.2, 1-26
  SCIE Scopus dColl.
• Prospective Pharmacological Potential of Resveratrol in Delaying Kidney Aging INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, v.22 no.15, 8258
  SCIE Scopus dColl.
• Prospects of Marine Sterols against Pathobiology of Alzheimer's Disease: Pharmacological Insights and Technological Advances Marine drugs, 2021, v.19 no.3, 0
  SCIE Scopus dColl.
• Protective Effects of Black Cumin (Nigella sativa) and Its Bioactive Constituent, Thymoquinone against Kidney Injury: An Aspect on Pharmacological Insights INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, v.22 no.16, 9078
  SCIE Scopus dColl.
• Evaluation of Anti-Tumor Effects of Whole-Body Low-Dose Irradiation in Metastatic Mouse Models CANCERS, 2020, v.12 no.5
  SCIE Scopus dColl.
• Fyn Kinase: A Potential Therapeutic Target in Acute Kidney Injury BIOMOLECULES & THERAPEUTICS, 2020, v.28 no.3, 213-221
  SCIE Scopus KCI dColl.
• Inhibition of src family kinases ameliorates lps-induced acute kidney injury and mitochondrial dysfunction in mice International Journal of Molecular Sciences, 2020, v.21 no.21, 1-17
  SCIE Scopus dColl.
• Recent Insights Into SREBP as a Direct Mediator of Kidney Fibrosis via Lipid-Independent Pathways FRONTIERS IN PHARMACOLOGY, 2020, v.11, 265
  SCIE Scopus dColl.
• The impaired redox balance in peroxisomes of catalase knockout mice accelerates nonalcoholic fatty liver disease through endoplasmic reticulum stress Free Radical Biology and Medicine, 2020, v.148, 22-32
  SCIE Scopus dColl.
• Urinary Metabolomic Profiling in Streptozotocin-Induced Diabetic Mice after Treatment with Losartan INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, v.21 no.23, 8969
  SCIE Scopus dColl.
• 성인지적 성건강의 융복합적 모형개발: 성인지 지표에 기반한 Sustainable Development Goals 국가와 북한과의 비교 연구 한국모자보건학회지, 2020, v.24 no.1, 40-51
  KCI dColl.
• Ablation of catalase promotes non-alcoholic fatty liver via oxidative stress and mitochondrial dysfunction in diet-induced obese mice PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 2019, v.471 no.6, 829-843
  SCIE Scopus dColl.
• Autophagy attenuates tubulointerstital fibrosis through regulating transforming growth factor-β and NLRP3 inflammasome signaling pathway Cell Death and Disease, 2019, v.10 no.2, 78
  SCIE Scopus dColl.
• Cigarette smoke inhalation aggravates diabetic kidney injury in rats TOXICOLOGY RESEARCH, 2019, v.8 no.6, 964-971
  SCIE Scopus dColl.
• Correlation study between A(3) adenosine receptor binding affinity and anti-renal interstitial fibrosis activity of truncated adenosine derivatives ARCHIVES OF PHARMACAL RESEARCH, 2019, v.42 no.9, 773-779
  SCIE Scopus KCI dColl.
• Enrichment of Short-Chain Ceramides and Free Fatty Acids in the Skin Epidermis, Liver, and Kidneys of db/db Mice, a Type 2 Diabetes Mellitus Model BIOMOLECULES & THERAPEUTICS, 2019, v.27 no.5, 457-465
  SCIE Scopus KCI dColl.
• Impaired Peroxisomal Fitness in Obese Mice, a Vicious Cycle Exacerbating Adipocyte Dysfunction via Oxidative Stress Antioxidants and Redox Signaling, 2019, v.31 no.18, 1339-1351
  SCIE Scopus dColl.
• Inhibition of Karyopherin-2 Augments Radiation-Induced Cell Death by Perturbing BRCA1-Mediated DNA Repair INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019, v.20 no.11, 2843
  SCIE Scopus dColl.
• Integrative omics reveals metabolic and transcriptomic alteration of nonalcoholic fatty liver disease in catalase knockout mice Biomolecules and Therapeutics, 2019, v.27 no.2, 134-144
  SCIE Scopus KCI dColl.
• Network-based integrated analysis of omics data reveal novel players ofTGF-beta 1-induced EMT in human peritoneal mesothelial cells SCIENTIFIC REPORTS, 2019, v.9, 1497
  SCIE Scopus dColl.
• PGC-1α, a potential therapeutic target against kidney aging Aging Cell, 2019, v.18 no.5, e12994
  Scopus dColl.
• Peroxiredoxin 3 deficiency accelerates chronic kidney injury in mice through interactions between macrophages and tubular epithelial cells Free Radical Biology and Medicine, 2019, v.131, 162-172
  SCIE Scopus dColl.
• Urinary myo-inositol is associated with the clinical outcome in focal segmental glomerulosclerosis Scientific Reports, 2019, v.9 no.1, 14707
  SCIE Scopus dColl.
• A pan-NADPH Oxidase Inhibitor Ameliorates Kidney Injury in Type 1 Diabetic Rats PHARMACOLOGY, 2018, v.102 no.3-4, 180-189
  SCIE Scopus dColl.
• Carbon monoxide releasing molecule-2 protects mice against acute kidney injury through inhibition of ER stress KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY, 2018, v.22 no.5, 567-575
  SCIE Scopus KCI dColl.
• Metabolic changes in urine and serum during progression of diabetic kidney disease in a mouse model ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2018, v.646, 90-97
  SCIE Scopus dColl.
• Orally active, species-independent novel A(3) adenosine receptor antagonist protects against kidney injury in db/db mice EXPERIMENTAL AND MOLECULAR MEDICINE, 2018, v.50
  SCIE Scopus KCI dColl.
• 8-Hydroxy-2-deoxyguanosine ameliorates high-fat diet-induced insulin resistance and adipocyte dysfunction in mice Biochemical and Biophysical Research Communications, 2017, v.491 no.4, 890-896
  SCIE Scopus dColl.
• A novel pan-Nox inhibitor, APX-115, protects kidney injury in streptozotocin-induced diabetic mice: possible role of peroxisomal and mitochondrial biogenesis ONCOTARGET, 2017, v.8 no.43, 74217-74232
  SCIE Scopus dColl.
• APX-115, a first-in-class pan-NADPH oxidase (Nox) inhibitor, protects db/db mice from renal injury LABORATORY INVESTIGATION, 2017, v.97 no.4, 419-431
  SCIE Scopus dColl.
• Delayed treatment with fenofibrate protects against high-fat diet-induced kidney injury in mice: the possible role of ampk autophagy American Journal of Physiology - Renal Physiology, 2017, v.312 no.2, F323-F334
  Scopus dColl.
• Effects of low-dose irradiation on mice with Escherichia coli-induced sepsis Toxicology and Applied Pharmacology, 2017, v.333, 17-25
  SCIE Scopus dColl.
• Endogenous catalase delays high-fat diet-induced liver injury in mice KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY, 2017, v.21 no.3, 317-325
  SCIE Scopus KCI dColl.
• TM5441, a plasminogen activator inhibitor-1 inhibitor, protects against high fat diet-induced non-alcoholic fatty liver disease ONCOTARGET, 2017, v.8 no.52, 89746-89760
  SCIE Scopus dColl.
• A novel plasminogen activator inhibitor-1 inhibitor, TM5441, protects against high-fat diet-induced obesity and adipocyte injury in mice BRITISH JOURNAL OF PHARMACOLOGY, 2016, v.173 no.17, 2622-2632
  SCIE Scopus dColl.
• Novel Plasminogen Activator Inhibitor-1 Inhibitors Prevent Diabetic Kidney Injury in a Mouse Model PLOS ONE, 2016, v.11 no.6
  SCIE Scopus dColl.
• Novel Role of Endogenous Catalase in Macrophage Polarization in Adipose Tissue MEDIATORS OF INFLAMMATION, 2016, v.2016
  SCIE Scopus dColl.
• Metformin Radiosensitizes p53-Deficient Colorectal Cancer Cells through Induction of G2/M Arrest and Inhibition of DNA Repair Proteins PLOS ONE, 2015, v.10 no.11
  SCIE Scopus dColl.
• Short-term Treatment of Daumone Improves Hepatic Inflammation in Aged Mice KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY, 2015, v.19 no.3, 269-274
  SCIE KCI Scopus dColl.
• 18β-glycyrrhetinic acid attenuates anandamide-induced adiposity and high-fat diet induced obesity Molecular Nutrition and Food Research, 2014, v.58 no.7, 1436-1446
  SCIE Scopus dColl.
• Clinical implication of allogenic implantation of adipogenic differentiated adipose-derived stem cells Stem Cells Translational Medicine, 2014, v.3 no.11, 1312-1322
  SCIE Scopus dColl.
• Daumone fed late in life improves survival and reduces hepatic inflammation and fibrosis in mice Aging Cell, 2014, v.13 no.4, 709-718
  Scopus dColl.
• EFFECT OF BIOCOMPATIBLE PERITONEAL DIALYSIS SOLUTION ON RESIDUAL RENAL FUNCTION: A SYSTEMATIC REVIEW OF RANDOMIZED CONTROLLED TRIALS PERITONEAL DIALYSIS INTERNATIONAL, 2014, v.34 no.7, 724-731
  SCIE Scopus dColl.
• Inhibitory role of the KEAP1-NRF2 pathway in TGFbβ1-stimulated renal epithelial transition to fibroblastic cells: A modulatory effect on SMAD signaling PLoS ONE, 2014, v.9 no.4
  SCIE Scopus dColl.
• Synthesis and Anti-Renal Fibrosis Activity of Conformationally Locked Truncated 2-Hexynyl-N-6-Substituted-(N)-Methanocarba-nucleosides as A(3) Adenosine Receptor Antagonists and Partial Agonists JOURNAL OF MEDICINAL CHEMISTRY, 2014, v.57 no.4, 1344-1354
  SCIE Scopus dColl.
• [학술지논문] Adenosine receptors as emerging therapeutic targets for diabetic kidney disease KIDNEY RESEARCH AND CLINICAL PRACTICE, 2022, v.41 no.0 , S74-S88
  SCIE
• [학술지논문] Kidney protective potential of lactoferrin: pharmacological insights and therapeutic advances KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY, 2022, v.26 no.1 , 1-13
  SCIE
• [학술지논문] Pan-Src kinase inhibitor treatment attenuates diabetic kidney injury via inhibition of Fyn kinase-mediated endoplasmic reticulum stress EXPERIMENTAL AND MOLECULAR MEDICINE, 2022, v.54 no.8 , 1086-1097
  SCI
• [학술지논문] Activation of beta(2) adrenergic receptor signaling modulates inflammation: a target limiting the progression of kidney diseases ARCHIVES OF PHARMACAL RESEARCH, 2021, v.44 no.1 , 49-62
  SCIE
• [학술지논문] Associations of Circulating Irisin with FNDC5 Expression in Fat and Muscle in Type 1 and Type 2 Diabetic Mice BIOMOLECULES, 2021, v.11 no.2 , 322-322
  SCIE
• [학술지논문] CO-Releasing Molecule-2 Prevents Acute Kidney Injury through Suppression of ROS-Fyn-ER Stress Signaling in Mouse Model OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2021, v.2021 no.0 , 994772-994772
  SCIE
• [학술지논문] Dojuksan ameliorates tubulointerstitial fibrosis through irisin-mediated muscle-kidney crosstalk PHYTOMEDICINE, 2021, v.80 no.0 , 153393-153393
  SCIE
• [학술지논문] Dual Actions of A(2A) and A(3) Adenosine Receptor Ligand Prevents Obstruction-Induced Kidney Fibrosis in Mice INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, v.22 no.11 , 5667-5667
  SCIE
• [학술지논문] Exercise-Induced Irisin Decreases Inflammation and Improves NAFLD by Competitive Binding with MD2 CELLS, 2021, v.10 no.12 , 3306-3306
  SCIE
• [학술지논문] Fumarate modulates phospholipase A2 receptor autoimmunity-induced podocyte injury in membranous nephropathy KIDNEY INTERNATIONAL, 2021, v.99 no.2 , 443-455
  SCI
• [학술지논문] Heukcha, naturally post-fermented green tea extract, ameliorates diet-induced hypercholesterolemia and NAFLD in hamster JOURNAL OF FOOD SCIENCE, 2021, v.86 no.11 , 5016-5025
  SCI
• [학술지논문] KF-1607, a Novel Pan Src Kinase Inhibitor, Attenuates Obstruction-Induced Tubulointerstitial Fibrosis in Mice BIOMOLECULES & THERAPEUTICS, 2021, v.29 no.1 , 41-51
  SCIE
• [학술지논문] Pharmacotherapy against Oxidative Stress in Chronic Kidney Disease: Promising Small Molecule Natural Products Targeting Nrf2-HO-1 Signaling Antioxidants, 2021, v.10 no.2 , 258-258
  SCIE
• [학술지논문] Prospective Pharmacological Potential of Resveratrol in Delaying Kidney Aging INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, v.22 no.15 , 8258-8258
  SCIE
• [학술지논문] Prospects of Marine Sterols against Pathobiology of Alzheimer's Disease: Pharmacological Insights and Technological Advances MARINE DRUGS, 2021, v.19 no.3 , 167-167
  SCIE
• [학술지논문] Protective Effects of Black Cumin (Nigella sativa) and Its Bioactive Constituent, Thymoquinone against Kidney Injury: An Aspect on Pharmacological Insights INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, v.22 no.16 , 9078-9078
  SCIE
• [학술지논문] Evaluation of Anti-Tumor Effects of Whole-Body Low-Dose Irradiation in Metastatic Mouse Models CANCERS, 2020, v.12 no.5 , 1126-1126
  SCIE
• [학술지논문] Fyn Kinase: A Potential Therapeutic Target in Acute Kidney Injury BIOMOLECULES & THERAPEUTICS, 2020, v.28 no.3 , 213-221
  SCIE
• [학술지논문] Inhibition of Src Family Kinases Ameliorates LPS-Induced Acute Kidney Injury and Mitochondrial Dysfunction in Mice INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, v.21 no.21 , 8246-8246
  SCIE
• [학술지논문] Recent Insights Into SREBP as a Direct Mediator of Kidney Fibrosis via Lipid-Independent Pathways FRONTIERS IN PHARMACOLOGY, 2020, v.11 no.0 , 265-265
  SCIE
• [학술지논문] The impaired redox balance in peroxisomes of catalase knockout mice accelerates nonalcoholic fatty liver disease through endoplasmic reticulum stress FREE RADICAL BIOLOGY AND MEDICINE, 2020, v.148 no.0 , 22-32
  SCI
• [학술지논문] Urinary Metabolomic Profiling in Streptozotocin-Induced Diabetic Mice after Treatment with Losartan INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, v.21 no.23 , 8969-8969
  SCIE
• [학술지논문] Ablation of catalase promotes non-alcoholic fatty liver via oxidative stress and mitochondrial dysfunction in diet-induced obese mice PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 2019, v.471 no.6 , 829-843
  SCI
• [학술지논문] Autophagy attenuates tubulointerstital fibrosis through regulating transforming growth factor-beta and NLRP3 inflammasome signaling pathway CELL DEATH & DISEASE, 2019, v.10 no.0 , 78-78
  SCIE
• [학술지논문] Cigarette smoke inhalation aggravates diabetic kidney injury in rats TOXICOLOGY RESEARCH, 2019, v.8 no.6 , 964-971
  SCIE
• [학술지논문] Correlation study between A(3) adenosine receptor binding affinity and anti-renal interstitial fibrosis activity of truncated adenosine derivatives ARCHIVES OF PHARMACAL RESEARCH, 2019, v.42 no.9 , 773-779
  SCIE
• [학술지논문] Impaired Peroxisomal Fitness in Obese Mice, a Vicious Cycle Exacerbating Adipocyte Dysfunction via Oxidative Stress ANTIOXIDANTS & REDOX SIGNALING, 2019, v.31 no.18 , 1339-1351
  SCI
• [학술지논문] Inhibition of Karyopherin-α2 Augments Radiation-Induced Cell Death by Perturbing BRCA1-Mediated DNA Repair INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019, v.20 no.11 , 2843-2843
  SCIE
• [학술지논문] Integrative Omics Reveals Metabolic and Transcriptomic Alteration of Nonalcoholic Fatty Liver Disease in Catalase Knockout Mice BIOMOLECULES & THERAPEUTICS, 2019, v.27 no.2 , 1-11
  SCIE
• [학술지논문] Network-based integrated analysis of omics data reveal novel players ofTGF-beta 1-induced EMT in human peritoneal mesothelial cells SCIENTIFIC REPORTS, 2019, v.9 no.0 , 1497-1497
  SCI
• [학술지논문] PGC-1 alpha, a potential therapeutic target against kidney aging Aging Cell, 2019, v.18 no.5 , 12994-12994
  SCIE
• [학술지논문] Peroxiredoxin 3 deficiency accelerates chronic kidney injury in mice through interactions between macrophages and tubular epithelial cells FREE RADICAL BIOLOGY AND MEDICINE, 2019, v.131 no.0 , 162-172
  SCI
• [학술지논문] Urinary myo-inositol is associated with the clinical outcome in focal segmental glomerulosclerosis SCIENTIFIC REPORTS, 2019, v.9 no.0 , 14707-14707
  SCI

Academic Background