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Ewha University

College of Medicine

Jung-hyuck Ahn Professor

College of Medicine

안정혁 프로필 사진

				
  • Chair, Department of Biochemistry
  • Esther Building #514
  • 02-6986-6200
Research Record
  • Epigenome-wide association study of diabetic chronic kidney disease progression in the Korean population: the KNOW-CKD study Scientific Reports, 2023, v.13 no.1, 8175
    SCIE Scopus dColl.
  • Identification of a novel PARP4 gene promoter CpG locus associated with cisplatin chemoresistance BMB REPORTS, 2023, v.56 no.6, 347-352
    SCIE Scopus KCI dColl.
  • Novel Genetic Variants Associated with Chronic Kidney Disease Progression Journal of the American Society of Nephrology : JASN, 2023, v.34 no.5, 857-875
    SCIE Scopus dColl.
  • Identification of Serum Metabolites for Predicting Chronic Kidney Disease Progression according to Chronic Kidney Disease Cause METABOLITES, 2022, v.12 no.11, 1125
    SCIE Scopus dColl.
  • Increased Caveolin-2 Expression in Brain Endothelial Cells Promotes Age-Related Neuroinflammation Molecules and Cells, 2022, v.45 no.12, 950-962
    SCIE Scopus KCI dColl.
  • Enhanced repair processes and iron uptake by ischemic preconditioning in the brain during the recovery phase after ischemic stroke BRAIN RESEARCH, 2021, v.1750, 147172
    SCIE Scopus dColl.
  • Protective role of ABCA1 in ischemic preconditioning is mediated by downregulation of miR-33-5p and miR-135-5p SCIENTIFIC REPORTS, 2021, v.11 no.1, 12511
    SCIE Scopus dColl.
  • Ahnak scaffolds p11/Anxa2 complex and L-type voltage-gated calcium channel and modulates depressive behavior MOLECULAR PSYCHIATRY, 2020, v.25 no.5, 1035-1049
    SCIE Scopus dColl.
  • Anti-inflammatory and antioxidant mechanisms of urolithin B in activated microglia Phytomedicine, 2019, v.55, 50-57
    SCIE Scopus dColl.
  • SPSB1 enhances ovarian cancer cell survival by destabilizing p21 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2019, v.510 no.3, 364-369
    SCIE Scopus dColl.
  • Aberrant Promoter Hypomethylation of Sortilin 1: A Moyamoya Disease Biomarker JOURNAL OF STROKE, 2018, v.20 no.3, 350-
    SCIE Scopus dColl.
  • C16-ceramide and sphingosine 1-phosphate/S1PR2 have opposite effects on cell growth through mTOR signaling pathway regulation ONCOLOGY REPORTS, 2018, v.40 no.5, 2977-2987
    SCIE Scopus dColl.
  • Effect of Necrosis on the miRNA-mRNA Regulatory Network in CRT-MG Human Astroglioma Cells CANCER RESEARCH AND TREATMENT, 2018, v.50 no.2, 382-397
    SCIE Scopus KCI dColl.
  • Epigenetic modification of alpha-N-acetylgalactosaminidase enhances cisplatin resistance in ovarian cancer KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY, 2018, v.22 no.1, 43-51
    SCIE Scopus KCI dColl.
  • Aberrant epigenetic regulation of GABRP associates with aggressive phenotype of ovarian cancer EXPERIMENTAL AND MOLECULAR MEDICINE, 2017, v.49
    SCIE Scopus KCI dColl.
  • Aberrant hypomethylation of solute carrier family 6 member 12 promoter induces metastasis of Ovarian cancer Yonsei Medical Journal, 2017, v.58 no.1, 27-34
    SCIE Scopus KCI dColl.
  • Ablation of ceramide synthase 2 exacerbates dextran sodium sulphate-induced colitis in mice due to increased intestinal permeability Journal of Cellular and Molecular Medicine, 2017, v.21 no.12, 3565-3578
    Scopus dColl.
  • Autophagy induction in the skeletal myogenic differentiation of human tonsil-derived mesenchymal stem cells INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2017, v.39 no.4, 831-840
    SCIE Scopus dColl.
  • Amyloid beta-mediated hypomethylation of heme oxygenase 1 correlates with cognitive impairment in Alzheimer's disease PLoS ONE, 2016, v.11 no.4
    SCIE Scopus dColl.
  • Modulation of NMDA Receptor Subunits Expression by Concanavalin A Neurochemical Research, 2016, 2 APR 2016, 1-12
    SCIE Scopus dColl.
  • Synaptotagmin-like protein 2 gene promotes the metastatic potential in ovarian cancer ONCOLOGY REPORTS, 2016, v.36 no.1, 535-541
    SCIE Scopus dColl.
  • APP intracellular domain-WAVE1 pathway reduces amyloid-β production Nature Medicine, 2015, v.21 no.9, 1054-1059
    SCIE Scopus dColl.
  • B56δ subunit of protein phosphatase 2A decreases phosphorylation of endothelial nitric oxide synthase at serine 116: Mechanism underlying aphidicolin-stimulated NO production Nitric Oxide - Biology and Chemistry, 2015, v.50, 46-51
    SCIE Scopus dColl.
  • Estrogen receptor-mediated resveratrol actions on blood-brain barrier of ovariectomized mice NEUROBIOLOGY OF AGING, 2015, v.36 no.2, 993-1006
    SCIE Scopus dColl.
  • Aberrant DNA methylation in the IFITM1 promoter enhances the metastatic phenotype in an intraperitoneal xenograft model of human ovarian cancer ONCOLOGY REPORTS, 2014, v.31 no.5, 2139-2146
    SCIE Scopus dColl.
  • Aberrant hypomethylation-mediated AGR2 overexpression induces an aggressive phenotype in ovarian cancer cells Oncology Reports, 2014, v.32 no.2, 815-820
    Scopus dColl.
  • Amyloid beta-mediated epigenetic alteration of insulin-like growth factor binding protein 3 controls cell survival in Alzheimer's Disease PLoS ONE, 2014, v.9 no.6
    SCIE Scopus dColl.
  • DNA hypomethylation-mediated overexpression of carbonic anhydrase 9 induces an aggressive phenotype in ovarian cancer cells Yonsei Medical Journal, 2014, v.55 no.6, 1656-1663
    SCIE KCI Scopus dColl.
  • Overexpression of Mucin 13 due to Promoter Methylation Promotes Aggressive Behavior in Ovarian Cancer Cells YONSEI MEDICAL JOURNAL, 2014, v.55 no.5, 1206-1213
    SCIE KCI Scopus dColl.
  • Regulatory B Subunits of Protein Phosphatase 2A Are Involved in Site-specific Regulation of Tau Protein Phosphorylation KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY, 2014, v.18 no.2, 155-161
    SCIE KCI Scopus dColl.
  • Role of T-reg and T(h)17 Cells of the Gastric Mucosa in Children With Helicobacter pylori Gastritis JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, 2014, v.58 no.2, 245-251
    SCIE Scopus dColl.
  • [학술지논문] Epigenome-wide association study of diabetic chronic kidney disease progression in the Korean population: the KNOW-CKD study SCIENTIFIC REPORTS, 2023, v.13 no.1 , 8175-8175
    SCIE
  • [학술지논문] Novel Genetic Variants Associated with Chronic Kidney Disease Progression JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2023, v.34 no.5 , 857-875
    SCIE
  • [학술지논문] Identification of Serum Metabolites for Predicting Chronic Kidney Disease Progression according to Chronic Kidney Disease Cause METABOLITES, 2022, v.12 no.11 , 1125-1125
    SCIE
  • [학술지논문] Enhanced repair processes and iron uptake by ischemic preconditioning in the brain during the recovery phase after ischemic stroke BRAIN RESEARCH, 2021, v.1750 no.0 , 147172-147172
    SCI
  • [학술지논문] Protective role of ABCA1 in ischemic preconditioning is mediated by downregulation of miR-33-5p and miR-135-5p SCIENTIFIC REPORTS, 2021, v.11 no.1 , 12511-12511
    SCI
  • [학술지논문] Ahnak scaffolds p11/Anxa2 complex and L-type voltage-gated calcium channel and modulates depressive behavior MOLECULAR PSYCHIATRY, 2020, v.25 no.5 , 1035-1049
    SCI
  • [학술지논문] Anti-inflammatory and antioxidant mechanisms of urolithin B in activated microglia PHYTOMEDICINE, 2019, v.55 no.0 , 50-57
    SCIE
  • [학술발표] Epigenetic Modification of Poly(ADP-Ribose) Polymerase Family Member 4 (PARP4) Enhances Cisplatin Resistance in Ovarian Cancer ICKSMCB2019, 대한민국, seoul, 2019-10-01 ICKSMCB2019, 2019
Courses
  • 2024-1st

    • Molecular Cell Biology Ⅰ 강의 계획서 상세보기

      • Subject No 34353Class No 01
      • 2Year ( 3Credit , 3Hour) Fri 4~5 (D)
      • Major Requisite
    • Introduction to Medicine

      • Subject No 37588Class No 01
      • 1Year ( 2.5Credit , 48Hour)
      • Major Requisite
    • Metabolism and Nutrition

      • Subject No 37594Class No 01
      • 1Year ( 2.5Credit , 52Hour)
      • Major Requisite
    • Thesis Writing

      • Subject No G14764Class No 01
      • Year ( 3Credit , 3Hour) Tue 8~9
    • Thesis Writing

      • Subject No G15683Class No 01
      • Year ( 3Credit , 3Hour) Tue 8~9
    • Biochemistry Seminar Ⅰ 강의 계획서 상세보기

      • Subject No G15719Class No 01
      • Year ( 3Credit , 3Hour) Tue 5~6
  • 2023-2nd

  • 2023-1st

    • Molecular Cell Biology Ⅰ 강의 계획서 상세보기

      • Subject No 34353Class No 01
      • 2Year ( 3Credit , 3Hour) Fri 4~5 (D)
      • Major Requisite
    • Introduction to Medicine

      • Subject No 37588Class No 01
      • 1Year ( 2.5Credit , 48Hour)
      • Major Requisite
    • Metabolism and Nutrition

      • Subject No 37594Class No 01
      • 1Year ( 2.5Credit , 52Hour)
      • Major Requisite
    • Thesis Writing

      • Subject No G14764Class No 01
      • Year ( 3Credit , 3Hour) Tue 8~9
    • Thesis Writing

      • Subject No G15683Class No 01
      • Year ( 3Credit , 3Hour) Tue 8~9
    • Biochemical Basis of Inherited Disease

      • Subject No G15724Class No 01
      • Year ( 3Credit , 3Hour) Tue 5~6
  • 2022-2nd

    • Human Genetics

      • Subject No 34736Class No 01
      • 2Year ( 3Credit , 3Hour) Wed 5~6 (D)
      • Major Requisite
    • Experiments in Molecular Cell Biology 

      • Subject No 38774Class No 01
      • 2Year ( 1Credit , 1.5Hour) Mon 5~6 (D)
      • Major Requisite
    • Experiments in Molecular Cell Biology 

      • Subject No 38774Class No 02
      • 2Year ( 1Credit , 1.5Hour) Mon 5~6 (D)
      • Major Requisite
    • Protein Biochemistry and Enzymology

      • Subject No G15787Class No 01
      • Year ( 3Credit , 3Hour) Tue 5~6
  • 2022-1st

    • Molecular Cell Biology Ⅰ

      • Subject No 34353Class No 01
      • 2Year ( 3Credit , 3Hour) Fri 3~4
      • Major Requisite
    • Introduction to Medicine

      • Subject No 37588Class No 01
      • 1Year ( 2.5Credit , 48Hour)
      • Major Requisite
    • Metabolism and Nutrition

      • Subject No 37594Class No 01
      • 1Year ( 2.5Credit , 52Hour)
      • Major Requisite
    • Thesis Writing

      • Subject No G14764Class No 01
      • Year ( 3Credit , 3Hour) Tue 8~9
    • Thesis Writing

      • Subject No G15683Class No 01
      • Year ( 3Credit , 3Hour) Tue 8~9
    • Cancer Biochemistry 강의 계획서 상세보기

      • Subject No G15721Class No 01
      • Year ( 3Credit , 3Hour) Tue 5~6
  • 2021-2nd

    • Human Genetics

      • Subject No 34736Class No 01
      • 2Year ( 3Credit , 3Hour) Tue 2~3 (D)
      • Major Requisite
    • Directed Individual Medical Research

      • Subject No 37500Class No 01
      • 2Year ( 2Credit , 2Hour) Fri 5~6 (D)
    • Experiments in Molecular Cell Biology 

      • Subject No 38774Class No 01
      • 2Year ( 1Credit , 1.5Hour) Wed 5~6 (D)
      • Major Requisite
    • Molecular Biology and Molecular Genetics

      • Subject No G14781Class No 01
      • Year ( 3Credit , 3Hour) Thu 7~8
    • Molecular Biology and Molecular Genetics

      • Subject No G15696Class No 01
      • Year ( 3Credit , 3Hour) Thu 7~8
  • 2021-1st

    • Molecular Cell Biology Ⅰ

      • Subject No 34353Class No 01
      • 2Year ( 3Credit , 3Hour) Wed 4~5
      • Major Requisite
    • Introduction to Medicine

      • Subject No 37588Class No 01
      • 1Year ( 2.5Credit , 48Hour)
      • Major Requisite
    • Metabolism and Nutrition

      • Subject No 37594Class No 01
      • 1Year ( 2.5Credit , 52Hour)
      • Major Requisite
    • Thesis Writing

      • Subject No G14764Class No 01
      • Year ( 3Credit , 3Hour) Tue 8~9
    • Seminars in Biomedical Science I

      • Subject No G14773Class No 01
      • Year ( 3Credit , 3Hour) Mon 7~8
    • Seminars in Biomedical Science III

      • Subject No G14774Class No 01
      • Year ( 3Credit , 3Hour) Mon 7~8
    • Thesis Writing

      • Subject No G15683Class No 01
      • Year ( 3Credit , 3Hour) Tue 8~9
    • Seminars in Biomedical Science I

      • Subject No G15691Class No 01
      • Year ( 3Credit , 3Hour) Mon 7~8
    • Seminars in Biomedical Science III

      • Subject No G15692Class No 01
      • Year ( 3Credit , 3Hour) Mon 7~8
    • Signal Transduction in Biochemistry

      • Subject No G15722Class No 01
      • Year ( 3Credit , 3Hour) Wed 5~6
Academic Background

Seoul Nat'l Univ. 의학박사(의학)

Work Experience

Chair, Department of Biochemistry 2016-08-01 ~ 2019-08-31

The Rockefeller Univ. 연구원 2002-04-01 ~ 2009-02-28

The Rockefeller Univ. 박사후연구원 2001-04-01 ~ 2003-03-31