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Ewha University

사범대학

양창원(梁彰院) 조교수

과학교육과

양창원 프로필 사진
양창원 교수는 사범대학 과학교육과(생물전공) 조교수로, 분자생체공학 전공으로 박사학위를 취득하였다. 난임 개선 및 임신기 질환 극복을 위한 분자 기전 연구, 세포외소포체 및 비암호화 RNA를 이용한 질환 진단 연구, 다양한 암 극복을 위한 치료 표적 발굴 연구, 환경오염 인자에 의한 독성 기전 연구 등을 분자세포생물학적인 관점에서 수행하였다. 현재는 비암호화 RNA의 조절에 의한 태반 발달의 분자 기전 연구와, 환경 노출에 의한 태아 프로그래밍을 기반으로 건강과 질병의 발생학적 기원에 대한 연구를 수행하고 있다.
  • 교육관 A동 504호
  • 02-3277-2688
  • 면담 가능시간
    • 화, 수 14:00~16:00
연구실적
  • [학술지논문] Sodium Butyrate Inhibits the Expression of Thymidylate Synthase and Induces Cell Death in Colorectal Cancer Cells INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, v.25 no.3 , 1572-1572
    SCIE
  • [학술지논문] Melatonin inhibits endometriosis development by disrupting mitochondrial function and regulating tiRNAs JOURNAL OF PINEAL RESEARCH, 2023, v.74 no.1 , 12842-12842
    SCIE
  • [학술지논문] Fraxetin induces cell death in colon cancer cells via mitochondria dysfunction and enhances therapeutic effects in 5-fluorouracil resistant cells JOURNAL OF CELLULAR BIOCHEMISTRY, 2022, v.123 no.2 , 469-480
    SCI
  • [학술지논문] Hesperidin Suppresses the Proliferation of Prostate Cancer Cells by Inducing Oxidative Stress and Disrupting Ca2+ Homeostasis ANTIOXIDANTS, 2022, v.11 no.9 , 1633-1633
    SCIE
  • [학술지논문] Inhibition of the cleaved half of tRNA(Gly) enhances palmitic acid-induced apoptosis in human trophoblasts JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2022, v.99 no.1 , 108866-108866
    SCI
  • [학술지논문] Palmitic acid induces inflammatory cytokines and regulates tRNA-derived stress-induced RNAs in human trophoblasts 한국동물생명공학회지, 2022, v.37 no.4 , 218-225
    KCI
  • [학술지논문] Targeting Thymidylate Synthase and tRNA-Derived Non-Coding RNAs Improves Therapeutic Sensitivity in Colorectal Cancer ANTIOXIDANTS, 2022, v.11 no.11 , 2158-2158
    SCIE
  • [학술지논문] Apigenin enhances apoptosis induction by 5-fluorouracil through regulation of thymidylate synthase in colorectal cancer cells REDOX BIOLOGY, 2021, v.47 no.1 , 102144-102144
    SCIE
  • [학술지논문] Eupatilin Impacts on the Progression of Colon Cancer by Mitochondria Dysfunction and Oxidative Stress ANTIOXIDANTS, 2021, v.10 no.6 , 957-957
    SCIE
  • [학술지논문] Identification of tissue-specific expression of CXCL14 in black rockfish (Sebastes schlegelii) FISH & SHELLFISH IMMUNOLOGY, 2021, v.112 no.1 , 135-142
    SCI
  • [학술지논문] Immunotoxicological effects of insecticides in exposed fishes COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY, 2021, v.247 no.1 , 109064-109064
    SCI
  • [학술지논문] Mechanisms of deleterious effects of some pesticide exposure on pigs PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 2021, v.175 no.1 , 104850-104850
    SCI
  • [학술지논문] Reproductive toxicity due to herbicide exposure in freshwater organisms COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY, 2021, v.248 no.1 , 109103-109103
    SCI
  • [학술지논문] tRNA(Lys)-Derived Fragment Alleviates Cisplatin-Induced Apoptosis in Prostate Cancer Cells PHARMACEUTICS, 2021, v.13 no.1 , 55-55
    SCIE
  • [학술지논문] A review of the toxicity in fish exposed to antibiotics COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY, 2020, v.237 no.1 , 108840-108840
    SCI
  • [학술지논문] Alterations in egg white-related genes expression in response to hormonal stimulation REPRODUCTION, 2020, v.160 no.5 , 793-801
    SCI
  • [학술지논문] Effects of endocrine disrupting chemicals in pigs ENVIRONMENTAL POLLUTION, 2020, v.263 no.2 , 114505-114505
    SCI
  • [학술지논문] Effects of mycotoxin-contaminated feed on farm animals JOURNAL OF HAZARDOUS MATERIALS, 2020, v.389 no.1 , 122087-122087
    SCI
  • [학술지논문] Eupatilin Promotes Cell Death by Calcium Influx through ER-Mitochondria Axis with SERPINB11 Inhibition in Epithelial Ovarian Cancer CANCERS, 2020, v.12 no.6 , 1459-1459
    SCIE
  • [학술지논문] Mediation of oxidative stress toxicity induced by pyrethroid pesticides in fish COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY, 2020, v.234 no.1 , 108758-108758
    SCI
  • [학술지논문] Melatonin improves uterine-conceptus interaction via regulation of SIRT1 during early pregnancy JOURNAL OF PINEAL RESEARCH, 2020, v.69 no.2 , 12670-12670
    SCI
  • [학술지논문] Methiothepin Suppresses Human Ovarian Cancer Cell Growth by Repressing Mitochondrion-Mediated Metabolism and Inhibiting Angiogenesis In Vivo PHARMACEUTICS, 2020, v.12 no.7 , 686-686
    SCIE
  • [학술지논문] Methiothepin mesylate causes apoptosis of human prostate cancer cells by mediating oxidative stress and mitochondrial dysfunction FREE RADICAL BIOLOGY AND MEDICINE, 2020, v.150 no.1 , 12-22
    SCI
  • [학술지논문] Quercetin Affects Spermatogenesis-Related Genes of Mouse Exposed to High-Cholesterol Diet 한국동물생명공학회지, 2020, v.35 no.1 , 73-85
    KCI
  • [학술지논문] 4-Methylbenzylidene-camphor inhibits proliferation and induces reactive oxygen species-mediated apoptosis of human trophoblast cells REPRODUCTIVE TOXICOLOGY, 2019, v.84 no.1 , 49-58
    SCI
  • [학술지논문] A mechanism for the effect of endocrine disrupting chemicals on placentation CHEMOSPHERE, 2019, v.231 no.1 , 326-336
    SCI
  • [학술지논문] Anti-inflammatory effects of mesenchymal stem cell-derived exosomal microRNA-146a-5p and microRNA-548e-5p on human trophoblast cells MOLECULAR HUMAN REPRODUCTION, 2019, v.25 no.11 , 755-+
    SCI
  • [학술지논문] Effects of extracellular vesicles on placentation and pregnancy disorders REPRODUCTION, 2019, v.158 no.5 , R189-R196
    SCI
  • [학술지논문] Inhibition of miR-214-3p Aids in Preventing Epithelial Ovarian Cancer Malignancy by Increasing the Expression of LHX6 CANCERS, 2019, v.11 no.12 , 1917-1917
    SCI
  • [학술지논문] The potential role of exosomes derived from ovarian cancer cells for diagnostic and therapeutic approaches JOURNAL OF CELLULAR PHYSIOLOGY, 2019, v.234 no.12 , 21493-21503
    SCI
  • [학술지논문] Avobenzone suppresses proliferative activity of human trophoblast cells and induces apoptosis mediated by mitochondrial disruption Check REPRODUCTIVE TOXICOLOGY, 2018, v.81 no.1 , 50-57
    SCI
  • [학술지논문] Butyl paraben promotes apoptosis in human trophoblast cells through increased oxidative stress-induced endoplasmic reticulum stress ENVIRONMENTAL TOXICOLOGY, 2018, v.33 no.4 , 436-445
    SCI
  • [학술지논문] C-C motif chemokine ligand 2 induces proliferation and prevents lipopolysaccharide-induced inflammatory responses in bovine mammary epithelial cells JOURNAL OF DAIRY SCIENCE, 2018, v.101 no.5 , 4527-4541
    SCI
  • [학술지논문] Decanoic acid suppresses proliferation and invasiveness of human trophoblast cells by disrupting mitochondrial function TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018, v.339 no.1 , 121-132
    SCI
  • [학술지논문] Down-regulation of stearoyl-CoA desaturase-1 increases susceptibility to palmitic-acid-induced lipotoxicity in human trophoblast cells JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2018, v.54 no.1 , 35-47
    SCI
  • [학술지논문] Homosalate aggravates the invasion of human trophoblast cells as well as regulates intracellular signaling pathways including PI3K/AKT and MAPK pathways ENVIRONMENTAL POLLUTION, 2018, v.243 no.1 , 1263-1273
    SCI
  • [학술지논문] Chrysophanol Induces Apoptosis of Choriocarcinoma Through Regulation of ROS and the AKT and ERK1/2 Pathways JOURNAL OF CELLULAR PHYSIOLOGY, 2017, v.232 no.2 , 331-339
    SCI
  • [학술지논문] Myricetin suppresses invasion and promotes cell death in human placental choriocarcinoma cells through induction of oxidative stress CANCER LETTERS, 2017, v.399 no.1 , 10-19
    SCI
  • [학술지논문] Oleic acid stimulation of motility of human extravillous trophoblast cells is mediated by stearoyl-CoA desaturase-1 activity MOLECULAR HUMAN REPRODUCTION, 2017, v.23 no.11 , 755-770
    SCI
  • [학술지논문] Propyl gallate induces cell death and inhibits invasion of human trophoblasts by blocking the AKT and mitogen-activated protein kinase pathways FOOD AND CHEMICAL TOXICOLOGY, 2017, v.109 no.1 , 497-504
    SCI
  • [학술지논문] Aquaporin 3 is regulated by estrogen in the chicken oviduct and is involved in progression of epithelial cell-derived ovarian carcinomas DOMESTIC ANIMAL ENDOCRINOLOGY, 2016, v.55 no.1 , 97-106
    SCI
  • [학술지논문] Luteolin Inhibits Proliferation and Induces Apoptosis of Human Placental Choriocarcinoma Cells by Blocking the PI3K/AKT Pathway and Regulating Sterol Regulatory Element Binding Protein Activity BIOLOGY OF REPRODUCTION, 2016, v.95 no.4 , 1-14
    SCI
  • [지적재산권] 부틸파라벤을 포함하는 임신성 영양막 질환 예방 또는 치료용 약학적 조성물(Pharmaceutical composition for preventing or treating gestational trophoblastic disease comprising butyl paraben) 국내 : 특허, 등록, 10-2201231-0000, 2021
  • [지적재산권] 4-MBC, 아보벤존 또는 이들의 혼합물을 포함하는 임신성 영양막 질환 예방 또는 치료용 약학적 조성물(Pharmaceutical composition for preventing or treating gestational trophoblastic disease comprising 4-MBC, avobenzone or mixture thereof) 국내 : 특허, 등록, 10-2141451-0000, 2020
  • [지적재산권] CCL2를 유효성분으로 포함하는 산유량 증가용 조성물, 및 유방염 예방 또는 치료용 약학적 조성물(Composition for improving milk yield comprising C-C motif chemokine ligand 2(CCL2), and Pharmaceutical composition for preventing or treating mastitis comprising the same) 국내 : 특허, 등록, 10-2154235-0000, 2020
  • [지적재산권] 데칸산을 포함하는 임신성 영양막 질환 예방 또는 치료용 약학적 조성물(Pharmaceutical composition for preventing or treating gestational trophoblastic disease comprising decanoic acid) 국내 : 특허, 등록, 10-2138840-0000, 2020
강의
  • 2024-1학기

  • 2023-2학기

    • 고급분자생물학 강의 계획서 상세보기

      • 학수번호 21959분반 01
      • 3학년 ( 3학점 , 3시간) 월 5~6 (교A313)
    • 세포학

      • 학수번호 21978분반 01
      • 2학년 ( 3학점 , 3시간) 금 4~5 (교A313)
      • 영어강의 화교2,지교2 [생교영역]
    • 분자세포생물학특론

      • 학수번호 G14451분반 01
      • 학년 ( 3학점 , 3시간) 목 8~9 (교A313)
    • 생물학특론

      • 학수번호 BI151분반 01
      • 학년 ( 3학점 , 3시간) 월 8~9 (교)
  • 2023-1학기

    • 1학년세미나(사범대) 강의 계획서 상세보기

      • 학수번호 10857분반 25
      • 1학년 ( 1학점 수 7~7 (교)
      • 생활 속의 생명과학
    • 분자세포생물학

    • 세포학

      • 학수번호 21978분반 01
      • 2학년 ( 3학점 , 3시간) 월 5~6 (교)
      • 영어강의 [생교영역] 물교2,생교2
    • 분자생물학교육

      • 학수번호 G14383분반 01
      • 학년 ( 3학점 , 3시간) 월 8~9 (교A313)
  • 2022-2학기

    • 고급분자생물학

      • 학수번호 21959분반 01
      • 3학년 ( 3학점 , 3시간) 목 2~3 (교A313)
    • 세포학

      • 학수번호 21978분반 01
      • 2학년 ( 3학점 , 3시간) 수 5~6 (교A414)
      • 화교2,지교2 [생교영역]
학력

고려대학교(서울) 이학박사(생명공학과)

고려대학교(서울) 이학사(생명공학부)